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A simulative deep learning model of SNP interactions on chromosome 19 for predicting Alzheimer's disease risk and rates of disease progression.
Bae J, Logan PE, Acri DJ, Bharthur A, Nho K, Saykin AJ, Risacher SL, Nudelman K, Polsinelli AJ, Pentchev V, Kim J, Hammers DB, Apostolova LG; Alzheimer's Disease Neuroimaging Initiative. Bae J, et al. Alzheimers Dement. 2023 Dec;19(12):5690-5699. doi: 10.1002/alz.13319. Epub 2023 Jul 6. Alzheimers Dement. 2023. PMID: 37409680
Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study.
Boerwinkle AH, Gordon BA, Wisch J, Flores S, Henson RL, Butt OH, McKay N, Chen CD, Benzinger TLS, Fagan AM, Handen BL, Christian BT, Head E, Mapstone M, Rafii MS, O'Bryant S, Lai F, Rosas HD, Lee JH, Silverman W, Brickman AM, Chhatwal JP, Cruchaga C, Perrin RJ, Xiong C, Hassenstab J, McDade E, Bateman RJ, Ances BM; Alzheimer's Biomarker Consortium-Down Syndrome; Dominantly Inherited Alzheimer Network. Boerwinkle AH, et al. Lancet Neurol. 2023 Jan;22(1):55-65. doi: 10.1016/S1474-4422(22)00408-2. Lancet Neurol. 2023. PMID: 36517172 Free PMC article.
Early-stage Alzheimer disease: getting trial-ready.
Aisen PS, Jimenez-Maggiora GA, Rafii MS, Walter S, Raman R. Aisen PS, et al. Nat Rev Neurol. 2022 Jul;18(7):389-399. doi: 10.1038/s41582-022-00645-6. Epub 2022 Apr 4. Nat Rev Neurol. 2022. PMID: 35379951 Free PMC article. Review.