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Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression.
Qin L, Berk M, Chung YM, Cui D, Zhu Z, Chakraborty AA, Sharifi N. Qin L, et al. Cell Rep. 2024 Jan 23;43(1):113575. doi: 10.1016/j.celrep.2023.113575. Epub 2024 Jan 4. Cell Rep. 2024. PMID: 38181788 Free PMC article.
Intratumoral androgen biosynthesis associated with 3β-hydroxysteroid dehydrogenase 1 promotes resistance to radiotherapy in prostate cancer.
Ganguly S, Lone Z, Muskara A, Imamura J, Hardaway A, Patel M, Berk M, Smile TD, Davicioni E, Stephans KL, Ciezki J, Weight CJ, Gupta S, Reddy CA, Tendulkar RD, Chakraborty AA, Klein EA, Sharifi N, Mian OY. Ganguly S, et al. J Clin Invest. 2023 Nov 15;133(22):e165718. doi: 10.1172/JCI165718. J Clin Invest. 2023. PMID: 37966114 Free PMC article.
BMX controls 3βHSD1 and sex steroid biosynthesis in cancer.
Li X, Berk M, Goins C, Alyamani M, Chung YM, Wang C, Patel M, Rathi N, Zhu Z, Willard B, Stauffer S, Klein E, Sharifi N. Li X, et al. J Clin Invest. 2023 Jan 17;133(2):e163498. doi: 10.1172/JCI163498. J Clin Invest. 2023. PMID: 36647826 Free PMC article.
H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer.
Baratchian M, Tiwari R, Khalighi S, Chakravarthy A, Yuan W, Berk M, Li J, Guerinot A, de Bono J, Makarov V, Chan TA, Silverman RH, Stark GR, Varadan V, De Carvalho DD, Chakraborty AA, Sharifi N. Baratchian M, et al. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2114324119. doi: 10.1073/pnas.2114324119. Epub 2022 May 18. Proc Natl Acad Sci U S A. 2022. PMID: 35584120 Free PMC article.
11 results