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Immune cells and their inflammatory mediators modify β cells and cause checkpoint inhibitor-induced diabetes.
Perdigoto AL, Deng S, Du KC, Kuchroo M, Burkhardt DB, Tong A, Israel G, Robert ME, Weisberg SP, Kirkiles-Smith N, Stamatouli AM, Kluger HM, Quandt Z, Young A, Yang ML, Mamula MJ, Pober JS, Anderson MS, Krishnaswamy S, Herold KC. Perdigoto AL, et al. JCI Insight. 2022 Sep 8;7(17):e156330. doi: 10.1172/jci.insight.156330. JCI Insight. 2022. PMID: 35925682 Free PMC article.
Indirect and Direct Effects of SARS-CoV-2 on Human Pancreatic Islets.
Ben Nasr M, D'Addio F, Montefusco L, Usuelli V, Loretelli C, Rossi A, Pastore I, Abdelsalam A, Maestroni A, Dell'Acqua M, Ippolito E, Assi E, Seelam AJ, Fiorina RM, Chebat E, Morpurgo P, Lunati ME, Bolla AM, Abdi R, Bonventre JV, Rusconi S, Riva A, Corradi D, Santus P, Clark P, Nebuloni M, Baldi G, Finzi G, Folli F, Zuccotti GV, Galli M, Herold KC, Fiorina P. Ben Nasr M, et al. Diabetes. 2022 Jul 1;71(7):1579-1590. doi: 10.2337/db21-0926. Diabetes. 2022. PMID: 35499468 Free PMC article.
Adverse events induced by immune checkpoint inhibitors.
Perdigoto AL, Kluger H, Herold KC. Perdigoto AL, et al. Curr Opin Immunol. 2021 Apr;69:29-38. doi: 10.1016/j.coi.2021.02.002. Epub 2021 Feb 25. Curr Opin Immunol. 2021. PMID: 33640598 Free PMC article. Review.