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2021 1
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Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity.
Zhong W, Lu Y, Han X, Yang J, Qin Z, Zhang W, Yu Z, Wu B, Liu S, Xu W, Zheng C, Schuchter LM, Karakousis GC, Mitchell TC, Amaravadi R, Flowers AJ, Gimotty PA, Xiao M, Mills G, Herlyn M, Dong H, Mitchell MJ, Kim J, Xu X, Guo W. Zhong W, et al. Cell Rep. 2023 Oct 31;42(10):113224. doi: 10.1016/j.celrep.2023.113224. Epub 2023 Oct 8. Cell Rep. 2023. PMID: 37805922 Free PMC article.
Stiff matrix induces exosome secretion to promote tumour growth.
Wu B, Liu DA, Guan L, Myint PK, Chin L, Dang H, Xu Y, Ren J, Li T, Yu Z, Jabban S, Mills GB, Nukpezah J, Chen YH, Furth EE, Gimotty PA, Wells RG, Weaver VM, Radhakrishnan R, Wang XW, Guo W. Wu B, et al. Nat Cell Biol. 2023 Mar;25(3):415-424. doi: 10.1038/s41556-023-01092-1. Epub 2023 Feb 16. Nat Cell Biol. 2023. PMID: 36797475 Free PMC article.
Immunosuppressive Extracellular Vesicles in CLL.
Zhong W, Guo W. Zhong W, et al. Blood Cancer Discov. 2023 Jan 6;4(1):5-7. doi: 10.1158/2643-3230.BCD-22-0161. Blood Cancer Discov. 2023. PMID: 36455131 Free PMC article.
ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells.
Kai F, Ou G, Tourdot RW, Stashko C, Gaietta G, Swift MF, Volkmann N, Long AF, Han Y, Huang HH, Northey JJ, Leidal AM, Viasnoff V, Bryant DM, Guo W, Wiita AP, Guo M, Dumont S, Hanein D, Radhakrishnan R, Weaver VM. Kai F, et al. EMBO J. 2022 Sep 1;41(17):e109205. doi: 10.15252/embj.2021109205. Epub 2022 Jul 25. EMBO J. 2022. PMID: 35880301 Free PMC article.
HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+ T-cell infiltration into tumors.
Guan L, Wu B, Li T, Beer LA, Sharma G, Li M, Lee CN, Liu S, Yang C, Huang L, Frederick DT, Boland GM, Shao G, Svitkina TM, Cai KQ, Chen F, Dong MQ, Mills GB, Schuchter LM, Karakousis GC, Mitchell TC, Flaherty KT, Speicher DW, Chen YH, Herlyn M, Amaravadi RK, Xu X, Guo W. Guan L, et al. Nat Commun. 2022 Jul 14;13(1):4078. doi: 10.1038/s41467-022-31713-6. Nat Commun. 2022. PMID: 35835783 Free PMC article.
13 results