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Year Number of Results
2016 3
2017 8
2018 13
2019 5
2020 8
2021 5
2022 8
2023 5
2024 1

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51 results

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Page 1
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer.
Guarducci C, Nardone A, Russo D, Nagy Z, Heraud C, Grinshpun A, Zhang Q, Freelander A, Leventhal MJ, Feit A, Cohen Feit G, Feiglin A, Liu W, Hermida-Prado F, Kesten N, Ma W, De Angelis C, Morlando A, O'Donnell M, Naumenko S, Huang S, Nguyen QD, Huang Y, Malorni L, Bergholz JS, Zhao JJ, Fraenkel E, Lim E, Schiff R, Shapiro GI, Jeselsohn R. Guarducci C, et al. Clin Cancer Res. 2024 May 1;30(9):1889-1905. doi: 10.1158/1078-0432.CCR-23-2975. Clin Cancer Res. 2024. PMID: 38381406 Free PMC article.
PI3Kβ controls immune evasion in PTEN-deficient breast tumours.
Bergholz JS, Wang Q, Wang Q, Ramseier M, Prakadan S, Wang W, Fang R, Kabraji S, Zhou Q, Gray GK, Abell-Hart K, Xie S, Guo X, Gu H, Von T, Jiang T, Tang S, Freeman GJ, Kim HJ, Shalek AK, Roberts TM, Zhao JJ. Bergholz JS, et al. Nature. 2023 May;617(7959):139-146. doi: 10.1038/s41586-023-05940-w. Epub 2023 Apr 19. Nature. 2023. PMID: 37076617 Free PMC article.
PI(3,5)P 2 Controls the Signaling Activity of Class I PI3K.
Sun J, Song S, Singaram I, Sharma A, Wang W, Hu Y, Lo WT, Koch PA, Zhao JJ, Haucke V, Gao R, Cho W. Sun J, et al. bioRxiv [Preprint]. 2023 Jan 25:2023.01.25.525550. doi: 10.1101/2023.01.25.525550. bioRxiv. 2023. PMID: 36747849 Free PMC article. Preprint.
STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer.
Ding L, Wang Q, Martincuks A, Kearns MJ, Jiang T, Lin Z, Cheng X, Qian C, Xie S, Kim HJ, Launonen IM, Färkkilä A, Roberts TM, Freeman GJ, Liu JF, Konstantinopoulos PA, Matulonis U, Yu H, Zhao JJ. Ding L, et al. J Immunother Cancer. 2023 Jan;11(1):e005627. doi: 10.1136/jitc-2022-005627. J Immunother Cancer. 2023. PMID: 36609487 Free PMC article.
Preclinical and Clinical Efficacy of Trastuzumab Deruxtecan in Breast Cancer Brain Metastases.
Kabraji S, Ni J, Sammons S, Li T, Van Swearingen AED, Wang Y, Pereslete A, Hsu L, DiPiro PJ, Lascola C, Moore H, Hughes M, Raghavendra AS, Gule-Monroe M, Murthy RK, Winer EP, Anders CK, Zhao JJ, Lin NU. Kabraji S, et al. Clin Cancer Res. 2023 Jan 4;29(1):174-182. doi: 10.1158/1078-0432.CCR-22-1138. Clin Cancer Res. 2023. PMID: 36074155 Free PMC article.
STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer.
Wang Q, Bergholz JS, Ding L, Lin Z, Kabraji SK, Hughes ME, He X, Xie S, Jiang T, Wang W, Zoeller JJ, Kim HJ, Roberts TM, Konstantinopoulos PA, Matulonis UA, Dillon DA, Winer EP, Lin NU, Zhao JJ. Wang Q, et al. Nat Commun. 2022 May 31;13(1):3022. doi: 10.1038/s41467-022-30568-1. Nat Commun. 2022. PMID: 35641483 Free PMC article.
Targeting CDK4 and CDK6 in cancer.
Goel S, Bergholz JS, Zhao JJ. Goel S, et al. Nat Rev Cancer. 2022 Jun;22(6):356-372. doi: 10.1038/s41568-022-00456-3. Epub 2022 Mar 18. Nat Rev Cancer. 2022. PMID: 35304604 Free PMC article. Review.
51 results