R35 CA197616/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2010	1
2011	1
2013	1
2014	2
2017	4
2018	12
2019	8
2020	11
2021	12
2022	7
2023	11
2024	3

1

p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.

Morral C, Ayyaz A, Kuo HC, Fink M, Verginadis II, Daniel AR, Burner DN, Driver LM, Satow S, Hasapis S, Ghinnagow R, Luo L, Ma Y, Attardi LD, Koumenis C, Minn AJ, Wrana JL, Lee CL, Kirsch DG. Morral C, et al. Nat Commun. 2024 Apr 8;15(1):3018. doi: 10.1038/s41467-024-47124-8. Nat Commun. 2024. PMID: 38589357 Free PMC article.

2

Spontaneous expression of the CIC::DUX4 fusion oncoprotein from a conditional allele potently drives sarcoma formation in genetically engineered mice.

Hendrickson PG, Oristian KM, Browne MR, Luo L, Ma Y, Cardona DM, Nash JO, Ballester PL, Davidson S, Shlien A, Linardic CM, Kirsch DG. Hendrickson PG, et al. Oncogene. 2024 Apr;43(16):1223-1230. doi: 10.1038/s41388-024-02984-8. Epub 2024 Feb 27. Oncogene. 2024. PMID: 38413794 Free PMC article.

3

Enhancing radiotherapy response via intratumoral injection of the TLR9 agonist CpG to stimulate CD8 T cells in an autochthonous mouse model of sarcoma.

Su C, Kent CL, Pierpoint M, Floyd W, Luo L, Wiliams NT, Ma Y, Peng B, Lazarides AL, Subramanian A, Himes JE, Perez VM, Hernansaiz-Ballesteros RD, Roche KE, Modliszewski JL, Selitsky SR, Mari Shinohara, Wisdom AJ, Moding EJ, Mowery YM, Kirsch DG. Su C, et al. bioRxiv [Preprint]. 2024 Jan 4:2024.01.03.573968. doi: 10.1101/2024.01.03.573968. bioRxiv. 2024. PMID: 38260522 Free PMC article. Preprint.

4

Radiation-induced bone loss in mice is ameliorated by inhibition of HIF-2α in skeletal progenitor cells.

Guo W, Hoque J, Garcia Garcia CJ, Spiller KV, Leinroth AP, Puviindran V, Potnis CK, Gunn KA, Newman H, Ishikawa K, Fujimoto TN, Neill DW, Delahoussaye AM, Williams NT, Kirsch DG, Hilton MJ, Varghese S, Taniguchi CM, Wu C. Guo W, et al. Sci Transl Med. 2023 Nov 29;15(724):eabo5217. doi: 10.1126/scitranslmed.abo5217. Epub 2023 Nov 29. Sci Transl Med. 2023. PMID: 38019933 Free PMC article.

5

Loss of function of Atrx leads to activation of alternative lengthening of telomeres in a primary mouse model of sarcoma.

Pierpoint M, Floyd W, Wisdom AJ, Luo L, Ma Y, Waitkus MS, Kirsch DG. Pierpoint M, et al. bioRxiv [Preprint]. 2023 Nov 6:2023.11.06.565874. doi: 10.1101/2023.11.06.565874. bioRxiv. 2023. PMID: 37986934 Free PMC article. Preprint.

6

Temporary Knockdown of p53 During Focal Limb Irradiation Increases the Development of Sarcomas.

Daniel AR, Su C, Williams NT, Li Z, Huang J, Lopez O, Luo L, Ma Y, Campos LDS, Selitsky SR, Modliszewski JL, Liu S, Hernansaiz-Ballesteros R, Mowery YM, Cardona DM, Lee CL, Kirsch DG. Daniel AR, et al. Cancer Res Commun. 2023 Dec 5;3(12):2455-2467. doi: 10.1158/2767-9764.CRC-23-0104. Cancer Res Commun. 2023. PMID: 37982576 Free PMC article.

7

Expression of the CIC-DUX4 fusion oncoprotein mimics human CIC-rearranged sarcoma in genetically engineered mouse models.

Hendrickson PG, Oristian KM, Browne MR, Luo L, Ma Y, Cardona DM, Linardic CM, Kirsch DG. Hendrickson PG, et al. Res Sq [Preprint]. 2023 Oct 29:rs.3.rs-3487637. doi: 10.21203/rs.3.rs-3487637/v1. Res Sq. 2023. PMID: 37961185 Free PMC article. Updated. Preprint.

8

Histological assessment of intestinal injury by ionizing radiation.

Kuo HC, Daniel AR, Driver LM, Lee CL, Kirsch DG. Kuo HC, et al. Methods Cell Biol. 2023;180:147-175. doi: 10.1016/bs.mcb.2023.03.001. Epub 2023 May 13. Methods Cell Biol. 2023. PMID: 37890927 Free PMC article.

9

Expression of the CIC-DUX4 fusion oncoprotein mimics human CIC-rearranged sarcoma in genetically engineered mouse models.

Hendrickson PG, Oristian KM, Browne MR, Lou L, Ma Y, Cardona DM, Linardic CM, Kirsch DG. Hendrickson PG, et al. bioRxiv [Preprint]. 2023 Sep 28:2023.09.26.559519. doi: 10.1101/2023.09.26.559519. bioRxiv. 2023. PMID: 37808628 Free PMC article. Updated. Preprint.

10

Mis-splicing Drives Loss of Function of p53^E224D Point Mutation.

Lock IC, Leisenring NH, Floyd W, Xu ES, Luo L, Ma Y, Mansell EC, Cardona DM, Lee CL, Kirsch DG. Lock IC, et al. bioRxiv [Preprint]. 2023 Aug 3:2023.08.01.551439. doi: 10.1101/2023.08.01.551439. bioRxiv. 2023. PMID: 37577531 Free PMC article. Preprint.

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