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The conformational landscape of human transthyretin revealed by cryo-EM.
Basanta B, Nugroho K, Yan NL, Kline GM, Powers ET, Tsai FJ, Wu M, Hansel-Harris A, Chen JS, Forli S, Kelly JW, Lander GC. Basanta B, et al. bioRxiv [Preprint]. 2024 Jan 23:2024.01.23.576879. doi: 10.1101/2024.01.23.576879. bioRxiv. 2024. PMID: 38328110 Free PMC article. Preprint.
Structure of the hepatitis C virus E1E2 glycoprotein complex.
Torrents de la Peña A, Sliepen K, Eshun-Wilson L, Newby ML, Allen JD, Zon I, Koekkoek S, Chumbe A, Crispin M, Schinkel J, Lander GC, Sanders RW, Ward AB. Torrents de la Peña A, et al. Science. 2022 Oct 21;378(6617):263-269. doi: 10.1126/science.abn9884. Epub 2022 Oct 20. Science. 2022. PMID: 36264808 Free PMC article.
Coupling of distant ATPase domains in the circadian clock protein KaiC.
Swan JA, Sandate CR, Chavan AG, Freeberg AM, Etwaru D, Ernst DC, Palacios JG, Golden SS, LiWang A, Lander GC, Partch CL. Swan JA, et al. Nat Struct Mol Biol. 2022 Aug;29(8):759-766. doi: 10.1038/s41594-022-00803-w. Epub 2022 Jul 21. Nat Struct Mol Biol. 2022. PMID: 35864165 Free PMC article.
Conquer by cryo-EM without physically dividing.
Lander GC, Glaeser RM. Lander GC, et al. Biochem Soc Trans. 2021 Nov 1;49(5):2287-2298. doi: 10.1042/BST20210360. Biochem Soc Trans. 2021. PMID: 34709401 Free PMC article. Review.