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Describing inhibitor specificity for the amino acid transporter LAT1 from metainference simulations.
Biophys J. 2022 Dec 6;121(23):4476-4491. doi: 10.1016/j.bpj.2022.11.001. Epub 2022 Nov 11.
Biophys J. 2022.
PMID: 36369754
Free PMC article.
The Effects of Prodrug Size and a Carbonyl Linker on l-Type Amino Acid Transporter 1-Targeted Cellular and Brain Uptake.
Venteicher B, Merklin K, Ngo HX, Chien HC, Hutchinson K, Campbell J, Way H, Griffith J, Alvarado C, Chandra S, Hill E, Schlessinger A, Thomas AA.
Venteicher B, et al.
ChemMedChem. 2021 Mar 3;16(5):869-880. doi: 10.1002/cmdc.202000824. Epub 2020 Dec 11.
ChemMedChem. 2021.
PMID: 33230949
Free PMC article.
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l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan.
Hall C, Wolfe H, Wells A, Chien HC, Colas C, Schlessinger A, Giacomini KM, Thomas AA.
Hall C, et al.
Bioorg Med Chem Lett. 2019 Aug 15;29(16):2254-2258. doi: 10.1016/j.bmcl.2019.06.033. Epub 2019 Jun 20.
Bioorg Med Chem Lett. 2019.
PMID: 31248771
Free PMC article.
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Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).
Chien HC, Colas C, Finke K, Springer S, Stoner L, Zur AA, Venteicher B, Campbell J, Hall C, Flint A, Augustyn E, Hernandez C, Heeren N, Hansen L, Anthony A, Bauer J, Fotiadis D, Schlessinger A, Giacomini KM, Thomas AA.
Chien HC, et al.
J Med Chem. 2018 Aug 23;61(16):7358-7373. doi: 10.1021/acs.jmedchem.8b01007. Epub 2018 Aug 10.
J Med Chem. 2018.
PMID: 30048132
Free PMC article.
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