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Page 1
Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.
Diabetologia. 2023 Jul;66(7):1260-1272. doi: 10.1007/s00125-023-05922-7. Epub 2023 May 26.
Diabetologia. 2023.
PMID: 37233759
Free PMC article.
Association of GLP1R Polymorphisms With the Incretin Response.
Dorsey-Trevino EG, Kaur V, Mercader JM, Florez JC, Leong A.
Dorsey-Trevino EG, et al.
J Clin Endocrinol Metab. 2022 Aug 18;107(9):2580-2588. doi: 10.1210/clinem/dgac374.
J Clin Endocrinol Metab. 2022.
PMID: 35723666
Free PMC article.
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A Polygenic Score for Type 2 Diabetes Risk Is Associated With Both the Acute and Sustained Response to Sulfonylureas.
Li JH, Szczerbinski L, Dawed AY, Kaur V, Todd JN, Pearson ER, Florez JC.
Li JH, et al.
Diabetes. 2021 Jan;70(1):293-300. doi: 10.2337/db20-0530. Epub 2020 Oct 26.
Diabetes. 2021.
PMID: 33106254
Free PMC article.
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The presence of two reduced function variants in CYP2C9 influences the acute response to glipizide.
Chen L, Li JH, Kaur V, Muhammad A, Fernandez M, Hudson MS, Goldfine AB, Florez JC.
Chen L, et al.
Diabet Med. 2020 Dec;37(12):2124-2130. doi: 10.1111/dme.14176. Epub 2019 Nov 25.
Diabet Med. 2020.
PMID: 31709648
Free PMC article.
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TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH).
Srinivasan S, Kaur V, Chamarthi B, Littleton KR, Chen L, Manning AK, Merino J, Thomas MK, Hudson M, Goldfine A, Florez JC.
Srinivasan S, et al.
Diabetes Care. 2018 Mar;41(3):554-561. doi: 10.2337/dc17-1386. Epub 2018 Jan 11.
Diabetes Care. 2018.
PMID: 29326107
Free PMC article.
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The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes.
Walford GA, Colomo N, Todd JN, Billings LK, Fernandez M, Chamarthi B, Warner AS, Davis J, Littleton KR, Hernandez AM, Fanelli RR, Lanier A, Barbato C, Ackerman RJ, Khan SQ, Bui R, Garber L, Stolerman ES, Moore AF, Huang C, Kaur V, Harden M, Taylor A, Chen L, Manning AK, Huang P, Wexler D, McCarthy RM, Lo J, Thomas MK, Grant RW, Goldfine A, Hudson MS, Florez JC.
Walford GA, et al.
PLoS One. 2015 Mar 26;10(3):e0121553. doi: 10.1371/journal.pone.0121553. eCollection 2015.
PLoS One. 2015.
PMID: 25812009
Free PMC article.
Clinical Trial.
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