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Cerebrospinal fluid mutant huntingtin is a biomarker for huntingtin lowering in the striatum of Huntington disease mice.
Neurobiol Dis. 2022 May;166:105652. doi: 10.1016/j.nbd.2022.105652. Epub 2022 Feb 7.
Neurobiol Dis. 2022.
PMID: 35143966
Free PMC article.
Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease.
Caron NS, Banos R, Yanick C, Aly AE, Byrne LM, Smith ED, Xie Y, Smith SEP, Potluri N, Findlay Black H, Casal L, Ko S, Cheung D, Kim H, Seong IS, Wild EJ, Song JJ, Hayden MR, Southwell AL.
Caron NS, et al.
J Neurosci. 2021 Jan 27;41(4):780-796. doi: 10.1523/JNEUROSCI.1865-20.2020. Epub 2020 Dec 11.
J Neurosci. 2021.
PMID: 33310753
Free PMC article.
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