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Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel JP, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Nature. 2024 Mar;627(8005):865-872. doi: 10.1038/s41586-024-07187-5. Epub 2024 Mar 20. Nature. 2024. PMID: 38509377
Interactions between immune cells recorded.
Wheeler MA. Wheeler MA. Nature. 2024 Mar;627(8003):277-279. doi: 10.1038/d41586-024-00426-9. Nature. 2024. PMID: 38448528 Free PMC article.
The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology.
Linnerbauer M, Lößlein L, Vandrey O, Peter A, Han Y, Tsaktanis T, Wogram E, Needhamsen M, Kular L, Nagel L, Zissler J, Andert M, Meszaros L, Hanspach J, Zuber F, Naumann UJ, Diebold M, Wheeler MA, Beyer T, Nirschl L, Cirac A, Laun FB, Günther C, Winkler J, Bäuerle T, Jagodic M, Hemmer B, Prinz M, Quintana FJ, Rothhammer V. Linnerbauer M, et al. Nat Immunol. 2024 Mar;25(3):432-447. doi: 10.1038/s41590-024-01756-6. Epub 2024 Feb 26. Nat Immunol. 2024. PMID: 38409259 Free PMC article.