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2020 2
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A lifelong duty: how Xist maintains the inactive X chromosome.
Jacobson EC, Pandya-Jones A, Plath K. Jacobson EC, et al. Curr Opin Genet Dev. 2022 Aug;75:101927. doi: 10.1016/j.gde.2022.101927. Epub 2022 Jun 16. Curr Opin Genet Dev. 2022. PMID: 35717799 Free PMC article. Review.
Xist nucleates local protein gradients to propagate silencing across the X chromosome.
Markaki Y, Chong JG, Wang Y, Jacobson EC, Luong C, Tan SYX, Jachowicz JW, Strehle M, Maestrini D, Banerjee AK, Mistry BA, Dror I, Dossin F, Schӧneberg J, Heard E, Guttman M, Chou T, Plath K. Markaki Y, et al. Cell. 2021 Dec 9;184(25):6212. doi: 10.1016/j.cell.2021.11.028. Cell. 2021. PMID: 34890555 Free PMC article. No abstract available.
Xist nucleates local protein gradients to propagate silencing across the X chromosome.
Markaki Y, Gan Chong J, Wang Y, Jacobson EC, Luong C, Tan SYX, Jachowicz JW, Strehle M, Maestrini D, Banerjee AK, Mistry BA, Dror I, Dossin F, Schöneberg J, Heard E, Guttman M, Chou T, Plath K. Markaki Y, et al. Cell. 2021 Dec 9;184(25):6174-6192.e32. doi: 10.1016/j.cell.2021.10.022. Epub 2021 Nov 4. Cell. 2021. PMID: 34813726 Free PMC article.
A protein assembly mediates Xist localization and gene silencing.
Pandya-Jones A, Markaki Y, Serizay J, Chitiashvili T, Mancia Leon WR, Damianov A, Chronis C, Papp B, Chen CK, McKee R, Wang XJ, Chau A, Sabri S, Leonhardt H, Zheng S, Guttman M, Black DL, Plath K. Pandya-Jones A, et al. Nature. 2020 Nov;587(7832):145-151. doi: 10.1038/s41586-020-2703-0. Epub 2020 Sep 9. Nature. 2020. PMID: 32908311 Free PMC article.
Regional Variation of Splicing QTLs in Human Brain.
Zhang Y, Yang HT, Kadash-Edmondson K, Pan Y, Pan Z, Davidson BL, Xing Y. Zhang Y, et al. Am J Hum Genet. 2020 Aug 6;107(2):196-210. doi: 10.1016/j.ajhg.2020.06.002. Epub 2020 Jun 25. Am J Hum Genet. 2020. PMID: 32589925 Free PMC article.