R01 HL148827/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2019	2
2020	2
2021	3
2022	2
2023	4
2024	0

1

Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity.

Birker K, Ge S, Kirkland NJ, Theis JL, Marchant J, Fogarty ZC, Missinato MA, Kalvakuri S, Grossfeld P, Engler AJ, Ocorr K, Nelson TJ, Colas AR, Olson TM, Vogler G, Bodmer R. Birker K, et al. Elife. 2023 Jul 5;12:e83385. doi: 10.7554/eLife.83385. Elife. 2023. PMID: 37404133 Free PMC article.

2

Multiplatform modeling of atrial fibrillation identifies phospholamban as a central regulator of cardiac rhythm.

Kervadec A, Kezos J, Ni H, Yu M, Marchant J, Spiering S, Kannan S, Kwon C, Andersen P, Bodmer R, Grandi E, Ocorr K, Colas AR. Kervadec A, et al. Dis Model Mech. 2023 Jul 1;16(7):dmm049962. doi: 10.1242/dmm.049962. Epub 2023 Jul 17. Dis Model Mech. 2023. PMID: 37293707 Free PMC article.

3

Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytes.

Kannan S, Miyamoto M, Zhu R, Lynott M, Guo J, Chen EZ, Colas AR, Lin BL, Kwon C. Kannan S, et al. Cell Rep. 2023 Apr 25;42(4):112330. doi: 10.1016/j.celrep.2023.112330. Epub 2023 Apr 3. Cell Rep. 2023. PMID: 37014753 Free PMC article.

4

Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells.

Missinato MA, Murphy S, Lynott M, Yu MS, Kervadec A, Chang YL, Kannan S, Loreti M, Lee C, Amatya P, Tanaka H, Huang CT, Puri PL, Kwon C, Adams PD, Qian L, Sacco A, Andersen P, Colas AR. Missinato MA, et al. Nat Commun. 2023 Mar 27;14(1):1709. doi: 10.1038/s41467-023-37256-8. Nat Commun. 2023. PMID: 36973293 Free PMC article.

5

Genetic architecture of natural variation of cardiac performance from flies to humans.

Saha S, Spinelli L, Castro Mondragon JA, Kervadec A, Lynott M, Kremmer L, Roder L, Krifa S, Torres M, Brun C, Vogler G, Bodmer R, Colas AR, Ocorr K, Perrin L. Saha S, et al. Elife. 2022 Nov 16;11:e82459. doi: 10.7554/eLife.82459. Elife. 2022. PMID: 36383075 Free PMC article.

6

Nascent polypeptide-Associated Complex and Signal Recognition Particle have cardiac-specific roles in heart development and remodeling.

Schroeder AM, Nielsen T, Lynott M, Vogler G, Colas AR, Bodmer R. Schroeder AM, et al. PLoS Genet. 2022 Oct 14;18(10):e1010448. doi: 10.1371/journal.pgen.1010448. eCollection 2022 Oct. PLoS Genet. 2022. PMID: 36240221 Free PMC article.

7

Temporal mechanisms of myogenic specification in human induced pluripotent stem cells.

Nayak P, Colas A, Mercola M, Varghese S, Subramaniam S. Nayak P, et al. Sci Adv. 2021 Mar 17;7(12):eabf7412. doi: 10.1126/sciadv.abf7412. Print 2021 Mar. Sci Adv. 2021. PMID: 33731358 Free PMC article.

8

PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2.

Murphy SA, Miyamoto M, Kervadec A, Kannan S, Tampakakis E, Kambhampati S, Lin BL, Paek S, Andersen P, Lee DI, Zhu R, An SS, Kass DA, Uosaki H, Colas AR, Kwon C. Murphy SA, et al. Nat Commun. 2021 Mar 12;12(1):1648. doi: 10.1038/s41467-021-21957-z. Nat Commun. 2021. PMID: 33712605 Free PMC article.

9

Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness.

Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J, Vadgama N, Quach J, McKeithan WL, Biechele TL, Wu JC, Moon RT, Si Dong PD, Karakikes I, Cashman JR, Mercola M. Cheng J, et al. Cell Chem Biol. 2021 May 20;28(5):625-635.e5. doi: 10.1016/j.chembiol.2021.01.001. Epub 2021 Jan 26. Cell Chem Biol. 2021. PMID: 33503403 Free PMC article.

10

Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome.

Theis JL, Vogler G, Missinato MA, Li X, Nielsen T, Zeng XI, Martinez-Fernandez A, Walls SM, Kervadec A, Kezos JN, Birker K, Evans JM, O'Byrne MM, Fogarty ZC, Terzic A, Grossfeld P, Ocorr K, Nelson TJ, Olson TM, Colas AR, Bodmer R. Theis JL, et al. Elife. 2020 Oct 2;9:e59554. doi: 10.7554/eLife.59554. Elife. 2020. PMID: 33006316 Free PMC article.

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