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2021 5
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Anomalous peroxidase activity of cytochrome c is the primary pathogenic target in Barth syndrome.
Kagan VE, Tyurina YY, Mikulska-Ruminska K, Damschroder D, Vieira Neto E, Lasorsa A, Kapralov AA, Tyurin VA, Amoscato AA, Samovich SN, Souryavong AB, Dar HH, Ramim A, Liang Z, Lazcano P, Ji J, Schmidtke MW, Kiselyov K, Korkmaz A, Vladimirov GK, Artyukhova MA, Rampratap P, Cole LK, Niyatie A, Baker EK, Peterson J, Hatch GM, Atkinson J, Vockley J, Kühn B, Wessells R, van der Wel PCA, Bahar I, Bayir H, Greenberg ML. Kagan VE, et al. Nat Metab. 2023 Dec;5(12):2184-2205. doi: 10.1038/s42255-023-00926-4. Epub 2023 Nov 23. Nat Metab. 2023. PMID: 37996701
NAD supplementation improves mitochondrial performance of cardiolipin mutants.
Ji J, Damschroder D, Bessert D, Lazcano P, Wessells R, Reynolds CA, Greenberg ML. Ji J, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Apr;1867(4):159094. doi: 10.1016/j.bbalip.2021.159094. Epub 2022 Jan 18. Biochim Biophys Acta Mol Cell Biol Lipids. 2022. PMID: 35051613 Free PMC article.
Studying Lipid-Related Pathophysiology Using the Yeast Model.
Ralph-Epps T, Onu CJ, Vo L, Schmidtke MW, Le A, Greenberg ML. Ralph-Epps T, et al. Front Physiol. 2021 Oct 28;12:768411. doi: 10.3389/fphys.2021.768411. eCollection 2021. Front Physiol. 2021. PMID: 34777024 Free PMC article. Review.
Direct Mapping of Phospholipid Ferroptotic Death Signals in Cells and Tissues by Gas Cluster Ion Beam Secondary Ion Mass Spectrometry (GCIB-SIMS).
Sparvero LJ, Tian H, Amoscato AA, Sun WY, Anthonymuthu TS, Tyurina YY, Kapralov O, Javadov S, He RR, Watkins SC, Winograd N, Kagan VE, Bayır H. Sparvero LJ, et al. Angew Chem Int Ed Engl. 2021 May 17;60(21):11784-11788. doi: 10.1002/anie.202102001. Epub 2021 Apr 12. Angew Chem Int Ed Engl. 2021. PMID: 33684237 Free PMC article.
Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal.
Sun WY, Tyurin VA, Mikulska-Ruminska K, Shrivastava IH, Anthonymuthu TS, Zhai YJ, Pan MH, Gong HB, Lu DH, Sun J, Duan WJ, Korolev S, Abramov AY, Angelova PR, Miller I, Beharier O, Mao GW, Dar HH, Kapralov AA, Amoscato AA, Hastings TG, Greenamyre TJ, Chu CT, Sadovsky Y, Bahar I, Bayır H, Tyurina YY, He RR, Kagan VE. Sun WY, et al. Nat Chem Biol. 2021 Apr;17(4):465-476. doi: 10.1038/s41589-020-00734-x. Epub 2021 Feb 4. Nat Chem Biol. 2021. PMID: 33542532 Free PMC article.