R01 GM110137/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 GM110137/GM/NIGMS NIH HHS/United States[Grant - PubMed

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Year	Number of Results
2015	1
2016	5
2017	5
2018	5
2019	4
2020	2
2021	1
2022	3
2023	4
2024	0

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Investigating the Cell Entry Mechanism, Disassembly, and Toxicity of the Nanocage PCC-1: Insights into Its Potential as a Drug Delivery Vehicle.

Xiao Z, Lin H, Drake HF, Diaz J, Zhou HC, Pellois JP. Xiao Z, et al. J Am Chem Soc. 2023 Dec 20;145(50):27690-27701. doi: 10.1021/jacs.3c09918. Epub 2023 Dec 9. J Am Chem Soc. 2023. PMID: 38069810 Free PMC article.

Deciphering variations in the endocytic uptake of a cell-penetrating peptide: the crucial role of cell culture protocols.

Diaz J, Pellois JP. Diaz J, et al. Cytotechnology. 2023 Dec;75(6):473-490. doi: 10.1007/s10616-023-00591-1. Epub 2023 Sep 8. Cytotechnology. 2023. PMID: 37841959

Elucidating the Impact of Payload Conjugation on the Cell-Penetrating Efficiency of the Endosomal Escape Peptide dfTAT: Implications for Future Designs for CPP-Based Delivery Systems.

Diaz J, Pietsch M, Davila M, Jaimes G, Hudson A, Pellois JP. Diaz J, et al. Bioconjug Chem. 2023 Oct 18;34(10):1861-1872. doi: 10.1021/acs.bioconjchem.3c00369. Epub 2023 Sep 29. Bioconjug Chem. 2023. PMID: 37774419 Free PMC article.

Lipids uniquely alter rates of insulin aggregation and lower toxicity of amyloid aggregates.

Matveyenka M, Rizevsky S, Pellois JP, Kurouski D. Matveyenka M, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Jan;1868(1):159247. doi: 10.1016/j.bbalip.2022.159247. Epub 2022 Oct 20. Biochim Biophys Acta Mol Cell Biol Lipids. 2023. PMID: 36272517 Free PMC article.

In vivo peptide-based delivery of a gene-modifying enzyme into cells of the central nervous system.

Allen JK, Sutherland TC, Prater AR, Geoffroy CG, Pellois JP. Allen JK, et al. Sci Adv. 2022 Sep 30;8(39):eabo2954. doi: 10.1126/sciadv.abo2954. Epub 2022 Sep 28. Sci Adv. 2022. PMID: 36170360 Free PMC article.

Hydrophobicity is a key determinant in the activity of arginine-rich cell penetrating peptides.

Allen J, Pellois JP. Allen J, et al. Sci Rep. 2022 Sep 25;12(1):15981. doi: 10.1038/s41598-022-20425-y. Sci Rep. 2022. PMID: 36156072 Free PMC article.

Superparamagnetic iron oxide-gold nanoparticles conjugated with porous coordination cages: Towards controlled drug release for non-invasive neuroregeneration.

Yuan M, Yan TH, Li J, Xiao Z, Fang Y, Wang Y, Zhou HC, Pellois JP. Yuan M, et al. Nanomedicine. 2021 Jul;35:102392. doi: 10.1016/j.nano.2021.102392. Epub 2021 Apr 16. Nanomedicine. 2021. PMID: 33872772 Free PMC article.

Impact of the Endosomal Escape Activity of Cell-Penetrating Peptides on the Endocytic Pathway.

Kondow-McConaghy HM, Muthukrishnan N, Erazo-Oliveras A, Najjar K, Juliano RL, Pellois JP. Kondow-McConaghy HM, et al. ACS Chem Biol. 2020 Sep 18;15(9):2355-2363. doi: 10.1021/acschembio.0c00319. Epub 2020 Aug 24. ACS Chem Biol. 2020. PMID: 32786263 Free PMC article.

Mechanism of Cell Penetration by Permeabilization of Late Endosomes: Interplay between a Multivalent TAT Peptide and Bis(monoacylglycero)phosphate.

Brock DJ, Kondow-McConaghy H, Allen J, Brkljača Z, Kustigian L, Jiang M, Zhang J, Rye H, Vazdar M, Pellois JP. Brock DJ, et al. Cell Chem Biol. 2020 Oct 15;27(10):1296-1307.e5. doi: 10.1016/j.chembiol.2020.07.015. Epub 2020 Aug 11. Cell Chem Biol. 2020. PMID: 32783962 Free PMC article.

Cytosolic Delivery of Macromolecules in Live Human Cells Using the Combined Endosomal Escape Activities of a Small Molecule and Cell Penetrating Peptides.

Allen J, Najjar K, Erazo-Oliveras A, Kondow-McConaghy HM, Brock DJ, Graham K, Hager EC, Marschall ALJ, Dübel S, Juliano RL, Pellois JP. Allen J, et al. ACS Chem Biol. 2019 Dec 20;14(12):2641-2651. doi: 10.1021/acschembio.9b00585. Epub 2019 Oct 31. ACS Chem Biol. 2019. PMID: 31633910 Free PMC article.

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