R01 GM090311/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2011	1
2012	3
2013	5
2014	2
2015	5
2016	7
2017	1
2018	1
2024	0

1

Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice.

Mao K, Quipildor GF, Tabrizian T, Novaj A, Guan F, Walters RO, Delahaye F, Hubbard GB, Ikeno Y, Ejima K, Li P, Allison DB, Salimi-Moosavi H, Beltran PJ, Cohen P, Barzilai N, Huffman DM. Mao K, et al. Nat Commun. 2018 Jun 19;9(1):2394. doi: 10.1038/s41467-018-04805-5. Nat Commun. 2018. PMID: 29921922 Free PMC article.

2

Subcellular Fractionation for ERK Activation Upon Mitochondrial-derived Peptide Treatment.

Kim SJ, Xiao J, Cohen P, Yen K. Kim SJ, et al. J Vis Exp. 2017 Sep 25;(127):56496. doi: 10.3791/56496. J Vis Exp. 2017. PMID: 28994791 Free PMC article.

3

The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus.

Kim SJ, Guerrero N, Wassef G, Xiao J, Mehta HH, Cohen P, Yen K. Kim SJ, et al. Oncotarget. 2016 Jul 26;7(30):46899-46912. doi: 10.18632/oncotarget.10380. Oncotarget. 2016. PMID: 27384491 Free PMC article.

4

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.

Mitchell SJ, Madrigal-Matute J, Scheibye-Knudsen M, Fang E, Aon M, González-Reyes JA, Cortassa S, Kaushik S, Gonzalez-Freire M, Patel B, Wahl D, Ali A, Calvo-Rubio M, Burón MI, Guiterrez V, Ward TM, Palacios HH, Cai H, Frederick DW, Hine C, Broeskamp F, Habering L, Dawson J, Beasley TM, Wan J, Ikeno Y, Hubbard G, Becker KG, Zhang Y, Bohr VA, Longo DL, Navas P, Ferrucci L, Sinclair DA, Cohen P, Egan JM, Mitchell JR, Baur JA, Allison DB, Anson RM, Villalba JM, Madeo F, Cuervo AM, Pearson KJ, Ingram DK, Bernier M, de Cabo R. Mitchell SJ, et al. Cell Metab. 2016 Jun 14;23(6):1093-1112. doi: 10.1016/j.cmet.2016.05.027. Cell Metab. 2016. PMID: 27304509 Free PMC article.

5

MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism.

Lee C, Kim KH, Cohen P. Lee C, et al. Free Radic Biol Med. 2016 Nov;100:182-187. doi: 10.1016/j.freeradbiomed.2016.05.015. Epub 2016 May 20. Free Radic Biol Med. 2016. PMID: 27216708 Free PMC article. Review.

6

Humanin: Functional Interfaces with IGF-I.

Xiao J, Kim SJ, Cohen P, Yen K. Xiao J, et al. Growth Horm IGF Res. 2016 Aug;29:21-27. doi: 10.1016/j.ghir.2016.03.005. Epub 2016 Apr 7. Growth Horm IGF Res. 2016. PMID: 27082450 Free PMC article. Review.

7

Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers.

Cobb LJ, Lee C, Xiao J, Yen K, Wong RG, Nakamura HK, Mehta HH, Gao Q, Ashur C, Huffman DM, Wan J, Muzumdar R, Barzilai N, Cohen P. Cobb LJ, et al. Aging (Albany NY). 2016 Apr;8(4):796-809. doi: 10.18632/aging.100943. Aging (Albany NY). 2016. PMID: 27070352 Free PMC article.

8

The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction.

Sreekumar PG, Ishikawa K, Spee C, Mehta HH, Wan J, Yen K, Cohen P, Kannan R, Hinton DR. Sreekumar PG, et al. Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1238-53. doi: 10.1167/iovs.15-17053. Invest Ophthalmol Vis Sci. 2016. PMID: 26990160 Free PMC article.

9

Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline.

Huffman DM, Farias Quipildor G, Mao K, Zhang X, Wan J, Apontes P, Cohen P, Barzilai N. Huffman DM, et al. Aging Cell. 2016 Feb;15(1):181-6. doi: 10.1111/acel.12415. Epub 2015 Nov 4. Aging Cell. 2016. PMID: 26534869 Free PMC article.

10

The Potent Humanin Analogue (HNG) Protects Germ Cells and Leucocytes While Enhancing Chemotherapy-Induced Suppression of Cancer Metastases in Male Mice.

Lue Y, Swerdloff R, Wan J, Xiao J, French S, Atienza V, Canela V, Bruhn KW, Stone B, Jia Y, Cohen P, Wang C. Lue Y, et al. Endocrinology. 2015 Dec;156(12):4511-21. doi: 10.1210/en.2015-1542. Epub 2015 Sep 18. Endocrinology. 2015. PMID: 26384090 Free PMC article.

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