R01 GM079656/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2007	1
2008	2
2009	5
2010	8
2011	4
2012	4
2013	9
2014	10
2015	7
2016	6
2017	10
2018	7
2019	12
2020	3
2021	6
2024	0

1

Identification of evolutionarily stable functional and immunogenic sites across the SARS-CoV-2 proteome and greater coronavirus family.

Wang C, Konecki DM, Marciano DC, Govindarajan H, Williams AM, Wastuwidyaningtyas B, Bourquard T, Katsonis P, Lichtarge O. Wang C, et al. Bioinformatics. 2021 Nov 18;37(22):4033-4040. doi: 10.1093/bioinformatics/btab406. Bioinformatics. 2021. PMID: 34043002 Free PMC article.

2

Using interpretable deep learning to model cancer dependencies.

Lin CH, Lichtarge O. Lin CH, et al. Bioinformatics. 2021 Sep 9;37(17):2675-2681. doi: 10.1093/bioinformatics/btab137. Bioinformatics. 2021. PMID: 34042953 Free PMC article.

3

A method to delineate de novo missense variants across pathways prioritizes genes linked to autism.

Koire A, Katsonis P, Kim YW, Buchovecky C, Wilson SJ, Lichtarge O. Koire A, et al. Sci Transl Med. 2021 May 19;13(594):eabc1739. doi: 10.1126/scitranslmed.abc1739. Sci Transl Med. 2021. PMID: 34011629 Free PMC article.

4

Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase.

Cea-Rama I, Coscolín C, Katsonis P, Bargiela R, Golyshin PN, Lichtarge O, Ferrer M, Sanz-Aparicio J. Cea-Rama I, et al. Comput Struct Biotechnol J. 2021 Apr 18;19:2307-2317. doi: 10.1016/j.csbj.2021.04.041. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 33995922 Free PMC article.

5

Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease.

Kim YW, Al-Ramahi I, Koire A, Wilson SJ, Konecki DM, Mota S, Soleimani S, Botas J, Lichtarge O. Kim YW, et al. Alzheimers Dement. 2021 May;17(5):831-846. doi: 10.1002/alz.12240. Epub 2020 Dec 7. Alzheimers Dement. 2021. PMID: 33576571 Free PMC article.

6

Identification of evolutionarily stable functional and immunogenic sites across the SARS-CoV-2 proteome and the greater coronavirus family.

Wang C, Konecki DM, Marciano DC, Govindarajan H, Williams AM, Wastuwidyaningtyas B, Bourquard T, Katsonis P, Lichtarge O. Wang C, et al. Res Sq [Preprint]. 2021 Feb 15:rs.3.rs-95030. doi: 10.21203/rs.3.rs-95030/v1. Res Sq. 2021. PMID: 33106800 Free PMC article. Updated. Preprint.

7

Graph-based information diffusion method for prioritizing functionally related genes in protein-protein interaction networks.

Pham M, Lichtarge O. Pham M, et al. Pac Symp Biocomput. 2020;25:439-450. Pac Symp Biocomput. 2020. PMID: 31797617 Free PMC article.

8

Discovery of disease- and drug-specific pathways through community structures of a literature network.

Pham M, Wilson S, Govindarajan H, Lin CH, Lichtarge O. Pham M, et al. Bioinformatics. 2020 Mar 1;36(6):1881-1888. doi: 10.1093/bioinformatics/btz857. Bioinformatics. 2020. PMID: 31738408 Free PMC article.

9

Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.

Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro G. Benredjem B, et al. Nat Commun. 2019 Sep 9;10(1):4075. doi: 10.1038/s41467-019-11875-6. Nat Commun. 2019. PMID: 31501422 Free PMC article.

10

Assessment of predicted enzymatic activity of α-N-acetylglucosaminidase variants of unknown significance for CAGI 2016.

Clark WT, Kasak L, Bakolitsa C, Hu Z, Andreoletti G, Babbi G, Bromberg Y, Casadio R, Dunbrack R, Folkman L, Ford CT, Jones D, Katsonis P, Kundu K, Lichtarge O, Martelli PL, Mooney SD, Nodzak C, Pal LR, Radivojac P, Savojardo C, Shi X, Zhou Y, Uppal A, Xu Q, Yin Y, Pejaver V, Wang M, Wei L, Moult J, Yu GK, Brenner SE, LeBowitz JH. Clark WT, et al. Hum Mutat. 2019 Sep;40(9):1519-1529. doi: 10.1002/humu.23875. Hum Mutat. 2019. PMID: 31342580 Free PMC article.

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