R01 ES030993/ES/NIEHS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	1
2021	8
2022	14
2023	20
2024	4

1

APOBEC shapes tumor evolution and age at onset of lung cancer in smokers.

Zhang T, Sang J, Hoang PH, Zhao W, Rosenbaum J, Johnson KE, Klimczak LJ, McElderry J, Klein A, Wirth C, Bergstrom EN, Díaz-Gay M, Vangara R, Colon-Matos F, Hutchinson A, Lawrence SM, Cole N, Zhu B, Przytycka TM, Shi J, Caporaso NE, Homer R, Pesatori AC, Consonni D, Imielinski M, Chanock SJ, Wedge DC, Gordenin DA, Alexandrov LB, Harris RS, Landi MT. Zhang T, et al. bioRxiv [Preprint]. 2024 Apr 3:2024.04.02.587805. doi: 10.1101/2024.04.02.587805. bioRxiv. 2024. PMID: 38617360 Free PMC article. Preprint.

2

Evaluating topography of mutational signatures with SigProfilerTopography.

Otlu B, Alexandrov LB. Otlu B, et al. bioRxiv [Preprint]. 2024 Jan 9:2024.01.08.574683. doi: 10.1101/2024.01.08.574683. bioRxiv. 2024. PMID: 38260507 Free PMC article. Preprint.

3

High UV damage and low repair, but not cytosine deamination, stimulate mutation hotspots at ETS binding sites in melanoma.

Duan M, Song S, Wasserman H, Lee PH, Liu KJ, Gordân R, He Y, Mao P. Duan M, et al. Proc Natl Acad Sci U S A. 2024 Jan 23;121(4):e2310854121. doi: 10.1073/pnas.2310854121. Epub 2024 Jan 19. Proc Natl Acad Sci U S A. 2024. PMID: 38241433

4

Comprehensive Pan-Cancer Mutation Density Patterns in Enhancer RNA.

Zhang T, Yu H, Jiang L, Bai Y, Liu X, Guo Y. Zhang T, et al. Int J Mol Sci. 2023 Dec 30;25(1):534. doi: 10.3390/ijms25010534. Int J Mol Sci. 2023. PMID: 38203707 Free PMC article.

5

Arsenic is a potent co-mutagen of ultraviolet light.

Speer RM, Nandi SP, Cooper KL, Zhou X, Yu H, Guo Y, Hudson LG, Alexandrov LB, Liu KJ. Speer RM, et al. Commun Biol. 2023 Dec 16;6(1):1273. doi: 10.1038/s42003-023-05659-4. Commun Biol. 2023. PMID: 38104187 Free PMC article.

6

Assigning mutational signatures to individual samples and individual somatic mutations with SigProfilerAssignment.

Díaz-Gay M, Vangara R, Barnes M, Wang X, Islam SMA, Vermes I, Duke S, Narasimman NB, Yang T, Jiang Z, Moody S, Senkin S, Brennan P, Stratton MR, Alexandrov LB. Díaz-Gay M, et al. Bioinformatics. 2023 Dec 1;39(12):btad756. doi: 10.1093/bioinformatics/btad756. Bioinformatics. 2023. PMID: 38096571 Free PMC article.

7

Arsenic and UVR co-exposure results in unique gene expression profile identifying key co-carcinogenic mechanisms.

Speer RM, Yu H, Zhou X, Nandi S, Alexandrov L, Guo Y, Hudson LG, Liu KJ. Speer RM, et al. Toxicol Appl Pharmacol. 2024 Jan;482:116773. doi: 10.1016/j.taap.2023.116773. Epub 2023 Nov 28. Toxicol Appl Pharmacol. 2024. PMID: 38036231 Free PMC article.

8

Pan-cancer mutational signature surveys correlated mutational signature with geospatial environmental exposures and viral infections.

Bai J, Ma K, Xia S, Geng R, Shen C, Jiang L, Gong X, Yu H, Leng S, Guo Y. Bai J, et al. Comput Struct Biotechnol J. 2023 Oct 20;21:5413-5422. doi: 10.1016/j.csbj.2023.10.041. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 38022689 Free PMC article.

9

Deep neural network based tissue deconvolution of circulating tumor cell RNA.

Yan F, Jiang L, Ye F, Ping J, Bowley TY, Ness SA, Li CI, Marchetti D, Tang J, Guo Y. Yan F, et al. J Transl Med. 2023 Nov 4;21(1):783. doi: 10.1186/s12967-023-04663-w. J Transl Med. 2023. PMID: 37925448 Free PMC article.

10

Mutation density analyses on long noncoding RNA reveal comparable patterns to protein-coding RNA and prognostic value.

Zhang T, Yu H, Bai Y, Guo Y. Zhang T, et al. Comput Struct Biotechnol J. 2023 Sep 25;21:4887-4894. doi: 10.1016/j.csbj.2023.09.027. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 37860228 Free PMC article.

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