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Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC.
Baer JM, Zuo C, Kang LI, de la Lastra AA, Borcherding NC, Knolhoff BL, Bogner SJ, Zhu Y, Yang L, Laurent J, Lewis MA, Zhang N, Kim KW, Fields RC, Yokoyama WM, Mills JC, Ding L, Randolph GJ, DeNardo DG. Baer JM, et al. Nat Immunol. 2023 Sep;24(9):1443-1457. doi: 10.1038/s41590-023-01579-x. Epub 2023 Aug 10. Nat Immunol. 2023. PMID: 37563309 Free PMC article.
Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia.
Lee SH, Kim N, Kim M, Woo SH, Han I, Park J, Kim K, Park KS, Kim K, Shim D, Park SE, Zhang JY, Go DM, Kim DY, Yoon WK, Lee SP, Chung J, Kim KW, Park JH, Lee SH, Lee S, Ann SJ, Lee SH, Ahn HS, Jeong SC, Kim TK, Oh GT, Park WY, Lee HO, Choi JH. Lee SH, et al. Nat Commun. 2022 Sep 17;13(1):5461. doi: 10.1038/s41467-022-33202-2. Nat Commun. 2022. PMID: 36115863 Free PMC article.
The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages.
Toboz P, Amiri M, Tabatabaei N, Dufour CR, Kim SH, Fillebeen C, Ayemoba CE, Khoutorsky A, Nairz M, Shao L, Pajcini KV, Kim KW, Giguère V, Oliveira RL, Constante M, Santos MM, Morales CR, Pantopoulos K, Sonenberg N, Pinho S, Tahmasebi S. Toboz P, et al. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2121251119. doi: 10.1073/pnas.2121251119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994670 Free PMC article.
Unravelling the sex-specific diversity and functions of adrenal gland macrophages.
Dolfi B, Gallerand A, Firulyova MM, Xu Y, Merlin J, Dumont A, Castiglione A, Vaillant N, Quemener S, Gerke H, Stunault MI, Schrank PR, Kim SH, Zhu A, Ding J, Gilleron J, Magnone V, Barbry P, Dombrowicz D, Duranton C, Wakkach A, Blin-Wakkach C, Becher B, Pagnotta S, Argüello RJ, Rantakari P, Chakarov S, Ginhoux F, Zaitsev K, Kim KW, Yvan-Charvet L, Guinamard RR, Williams JW, Ivanov S. Dolfi B, et al. Cell Rep. 2022 Jun 14;39(11):110949. doi: 10.1016/j.celrep.2022.110949. Cell Rep. 2022. PMID: 35705045 Free PMC article.