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2019 2
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2024 1

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Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury.
Varadharajan V, Ramachandiran I, Massey WJ, Jain R, Banerjee R, Horak AJ, McMullen MR, Huang E, Bellar A, Lorkowski SW, Gulshan K, Helsley RN, James I, Pathak V, Dasarathy J, Welch N, Dasarathy S, Streem D, Reizes O, Allende DS, Smith JD, Simcox J, Nagy LE, Brown JM. Varadharajan V, et al. Elife. 2024 Apr 22;12:RP92243. doi: 10.7554/eLife.92243. Elife. 2024. PMID: 38648183 Free PMC article.
Metaorganismal choline metabolism shapes olfactory perception.
Massey WJ, Kay KE, Jaramillo TC, Horak AJ 3rd, Cao S, Osborn LJ, Banerjee R, Mrdjen M, Hamoudi MK, Silver DJ, Burrows AC, Brown AL, Reizes O, Lathia JD, Wang Z, Hazen SL, Brown JM. Massey WJ, et al. J Biol Chem. 2023 Nov;299(11):105299. doi: 10.1016/j.jbc.2023.105299. Epub 2023 Sep 28. J Biol Chem. 2023. PMID: 37777156 Free PMC article.
MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis.
Phadnis VV, Snider J, Varadharajan V, Ramachandiran I, Deik AA, Lai ZW, Kunchok T, Eaton EN, Sebastiany C, Lyakisheva A, Vaccaro KD, Allen J, Yao Z, Wong V, Geng B, Weiskopf K, Clish CB, Brown JM, Stagljar I, Weinberg RA, Henry WS. Phadnis VV, et al. Cell Rep. 2023 Sep 26;42(9):113023. doi: 10.1016/j.celrep.2023.113023. Epub 2023 Sep 8. Cell Rep. 2023. PMID: 37691145 Free PMC article.
A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis.
Osborn LJ, Schultz K, Massey W, DeLucia B, Choucair I, Varadharajan V, Banerjee R, Fung K, Horak AJ 3rd, Orabi D, Nemet I, Nagy LE, Wang Z, Allende DS, Willard BB, Sangwan N, Hajjar AM, McDonald C, Ahern PP, Hazen SL, Brown JM, Claesen J. Osborn LJ, et al. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2202934119. doi: 10.1073/pnas.2202934119. Epub 2022 Nov 23. Proc Natl Acad Sci U S A. 2022. PMID: 36417437 Free PMC article.
31 results