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High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition.
Cell Rep. 2022 Jul 26;40(4):111095. doi: 10.1016/j.celrep.2022.111095.
Cell Rep. 2022.
PMID: 35905710
Free PMC article.
Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN-amplified neuroblastoma.
Dalton KM, Lochmann TL, Floros KV, Calbert ML, Kurupi R, Stein GT, McClanaghan J, Murchie E, Egan RK, Greninger P, Dozmorov M, Ramamoorthy S, Puchalapalli M, Hu B, Shock L, Koblinski J, Glod J, Boikos SA, Benes CH, Faber AC.
Dalton KM, et al.
Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2009620118. doi: 10.1073/pnas.2009620118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33762304
Free PMC article.
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