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2021 1
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Page 1
Enolase Inhibitors as Early Lead Therapeutics against Trypanosoma brucei.
Roster CP, LaVigne D, Milanes JE, Knight E, Anderson HD, Pizarro S, Harding EM, Morris MT, Yan VC, Pham CD, Muller F, Kwain S, Rees KC, Dominy B, Whitehead DC, Uddin MN, Millward SW, Morris JC. Roster CP, et al. Pathogens. 2023 Oct 28;12(11):1290. doi: 10.3390/pathogens12111290. Pathogens. 2023. PMID: 38003754 Free PMC article.
Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism.
Khadka S, Lin YH, Ackroyd J, Chen YA, Sheng Y, Qian W, Guo S, Chen Y, Behr E, Barekatain Y, Uddin N, Arthur K, Yan V, Hsu WH, Chang Q, Poral A, Tran T, Chaurasia S, Georgiou DK, Asara JM, Barthel FP, Millward SW, DePinho RA, Muller FL. Khadka S, et al. bioRxiv [Preprint]. 2023 Oct 19:2023.05.07.539744. doi: 10.1101/2023.05.07.539744. bioRxiv. 2023. PMID: 37214825 Free PMC article. Preprint.
Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers.
Yan VC, Pham CD, Ballato ES, Yang KL, Arthur K, Khadka S, Barekatain Y, Shrestha P, Tran T, Poral AH, Washington M, Raghavan S, Czako B, Pisaneschi F, Lin YH, Satani N, Hammoudi N, Ackroyd JJ, Georgiou DK, Millward SW, Muller FL. Yan VC, et al. J Med Chem. 2022 Oct 27;65(20):13813-13832. doi: 10.1021/acs.jmedchem.2c01039. Epub 2022 Oct 17. J Med Chem. 2022. PMID: 36251833 Free PMC article.
Directing evolution of novel ligands by mRNA display.
Kamalinia G , Grindel BJ , Takahashi TT , Millward SW , Roberts RW . Kamalinia G , et al. Chem Soc Rev. 2021 Aug 21;50(16):9055-9103. doi: 10.1039/d1cs00160d. Epub 2021 Jun 24. Chem Soc Rev. 2021. PMID: 34165126 Free PMC article. Review.