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2017 2
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2020 7
2021 6
2022 5
2024 0

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28 results

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Page 1
Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome.
Su H, Yang F, Fu R, Trinh B, Sun N, Liu J, Kumar A, Baglieri J, Siruno J, Le M, Li Y, Dozier S, Nair A, Filliol A, Sinchai N, Rosenthal SB, Santini J, Metallo CM, Molina A, Schwabe RF, Lowy AM, Brenner D, Sun B, Karin M. Su H, et al. Nature. 2022 Oct;610(7931):366-372. doi: 10.1038/s41586-022-05169-z. Epub 2022 Oct 5. Nature. 2022. PMID: 36198801 Free PMC article.
The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62.
Linares JF, Cid-Diaz T, Duran A, Osrodek M, Martinez-Ordoñez A, Reina-Campos M, Kuo HH, Elemento O, Martin ML, Cordes T, Thompson TC, Metallo CM, Moscat J, Diaz-Meco MT. Linares JF, et al. Cell Rep. 2022 May 10;39(6):110792. doi: 10.1016/j.celrep.2022.110792. Cell Rep. 2022. PMID: 35545049 Free PMC article.
PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis.
Linares JF, Zhang X, Martinez-Ordoñez A, Duran A, Kinoshita H, Kasashima H, Nakanishi N, Nakanishi Y, Carelli R, Cappelli L, Arias E, Yashiro M, Ohira M, Patel S, Inghirami G, Loda M, Cuervo AM, Diaz-Meco MT, Moscat J. Linares JF, et al. Mol Cell. 2021 Nov 4;81(21):4509-4526.e10. doi: 10.1016/j.molcel.2021.08.039. Epub 2021 Sep 23. Mol Cell. 2021. PMID: 34560002 Free PMC article.
Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis.
Su H, Yang F, Fu R, Li X, French R, Mose E, Pu X, Trinh B, Kumar A, Liu J, Antonucci L, Todoric J, Liu Y, Hu Y, Diaz-Meco MT, Moscat J, Metallo CM, Lowy AM, Sun B, Karin M. Su H, et al. Cancer Cell. 2021 May 10;39(5):678-693.e11. doi: 10.1016/j.ccell.2021.02.016. Epub 2021 Mar 18. Cancer Cell. 2021. PMID: 33740421 Free PMC article.
Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population.
Kasashima H, Duran A, Martinez-Ordoñez A, Nakanishi Y, Kinoshita H, Linares JF, Reina-Campos M, Kudo Y, L'Hermitte A, Yashiro M, Ohira M, Bao F, Tauriello DVF, Batlle E, Diaz-Meco MT, Moscat J. Kasashima H, et al. Dev Cell. 2021 Jan 11;56(1):95-110.e10. doi: 10.1016/j.devcel.2020.10.014. Epub 2020 Nov 17. Dev Cell. 2021. PMID: 33207226 Free PMC article.
28 results