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Year Number of Results
2016 5
2017 16
2018 6
2019 5
2020 7
2021 7
2022 2
2023 1
2024 0

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44 results

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Page 1
PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma.
Wartewig T, Daniels J, Schulz M, Hameister E, Joshi A, Park J, Morrish E, Venkatasubramani AV, Cernilogar FM, van Heijster FHA, Hundshammer C, Schneider H, Konstantinidis F, Gabler JV, Klement C, Kurniawan H, Law C, Lee Y, Choi S, Guitart J, Forne I, Giustinani J, Müschen M, Jain S, Weinstock DM, Rad R, Ortonne N, Schilling F, Schotta G, Imhof A, Brenner D, Choi J, Ruland J. Wartewig T, et al. Nat Cancer. 2023 Oct;4(10):1508-1525. doi: 10.1038/s43018-023-00635-7. Epub 2023 Sep 18. Nat Cancer. 2023. PMID: 37723306 Free PMC article.
Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses.
Contreras-Trujillo H, Eerdeng J, Akre S, Jiang D, Contreras J, Gala B, Vergel-Rodriguez MC, Lee Y, Jorapur A, Andreasian A, Harton L, Bramlett CS, Nogalska A, Xiao G, Lee JW, Chan LN, Müschen M, Merchant AA, Lu R. Contreras-Trujillo H, et al. Nat Commun. 2021 Nov 11;12(1):6522. doi: 10.1038/s41467-021-26771-1. Nat Commun. 2021. PMID: 34764253 Free PMC article.
Metabolic determinants of B-cell selection.
Chan LN, Aghania E, Leveille E, Müschen M. Chan LN, et al. Biochem Soc Trans. 2021 Jun 30;49(3):1467-1478. doi: 10.1042/BST20201316. Biochem Soc Trans. 2021. PMID: 34196360 Review.
Topography of transcriptionally active chromatin in glioblastoma.
Xu L, Chen Y, Huang Y, Sandanaraj E, Yu JS, Lin RY, Dakle P, Ke XY, Chong YK, Koh L, Mayakonda A, Nacro K, Hill J, Huang ML, Gery S, Lim SW, Huang Z, Xu Y, Chen J, Bai L, Wang S, Wakimoto H, Yeo TT, Ang BT, Müschen M, Tang C, Tan TZ, Koeffler HP. Xu L, et al. Sci Adv. 2021 Apr 30;7(18):eabd4676. doi: 10.1126/sciadv.abd4676. Print 2021 Apr. Sci Adv. 2021. PMID: 33931443 Free PMC article.
Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer.
Sadras T, Martin M, Kume K, Robinson ME, Saravanakumar S, Lenz G, Chen Z, Song JY, Siddiqi T, Oksa L, Knapp AM, Cutler J, Cosgun KN, Klemm L, Ecker V, Winchester J, Ghergus D, Soulas-Sprauel P, Kiefer F, Heisterkamp N, Pandey A, Ngo V, Wang L, Jumaa H, Buchner M, Ruland J, Chan WC, Meffre E, Martin T, Müschen M. Sadras T, et al. Mol Cell. 2021 May 20;81(10):2094-2111.e9. doi: 10.1016/j.molcel.2021.03.043. Epub 2021 Apr 19. Mol Cell. 2021. PMID: 33878293 Free PMC article.
PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis.
Pan L, Hong C, Chan LN, Xiao G, Malvi P, Robinson ME, Geng H, Reddy ST, Lee J, Khairnar V, Cosgun KN, Xu L, Kume K, Sadras T, Wang S, Wajapeyee N, Müschen M. Pan L, et al. Proc Natl Acad Sci U S A. 2021 Feb 16;118(7):e2016553118. doi: 10.1073/pnas.2016553118. Proc Natl Acad Sci U S A. 2021. PMID: 33531346 Free PMC article.
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis.
Qing Y, Dong L, Gao L, Li C, Li Y, Han L, Prince E, Tan B, Deng X, Wetzel C, Shen C, Gao M, Chen Z, Li W, Zhang B, Braas D, Ten Hoeve J, Sanchez GJ, Chen H, Chan LN, Chen CW, Ann D, Jiang L, Müschen M, Marcucci G, Plas DR, Li Z, Su R, Chen J. Qing Y, et al. Mol Cell. 2021 Mar 4;81(5):922-939.e9. doi: 10.1016/j.molcel.2020.12.026. Mol Cell. 2021. PMID: 33434505 Free PMC article.
Metabolic Gatekeepers of Pathological B Cell Activation.
Sadras T, Chan LN, Xiao G, Müschen M. Sadras T, et al. Annu Rev Pathol. 2021 Jan 24;16:323-349. doi: 10.1146/annurev-pathol-061020-050135. Epub 2020 Dec 15. Annu Rev Pathol. 2021. PMID: 33321055 Review.
44 results