R01 CA212608/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	2
2017	4
2018	3
2019	8
2020	8
2021	10
2022	6
2023	5
2024	0

1

mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection.

Ivanova EN, Shwetar J, Devlin JC, Buus TB, Gray-Gaillard S, Koide A, Cornelius A, Samanovic MI, Herrera A, Mimitou EP, Zhang C, Karmacharya T, Desvignes L, Ødum N, Smibert P, Ulrich RJ, Mulligan MJ, Koide S, Ruggles KV, Herati RS, Koralov SB. Ivanova EN, et al. iScience. 2023 Nov 24;26(12):108572. doi: 10.1016/j.isci.2023.108572. eCollection 2023 Dec 15. iScience. 2023. PMID: 38213787 Free PMC article.

2

Systematic Fe(II)-EDTA Method of Dose-Dependent Hydroxyl Radical Generation for Protein Oxidative Footprinting.

Chapman JR, Paukner M, Leser M, Teng KW, Koide S, Holder M, Armache KJ, Becker C, Ueberheide B, Brenowitz M. Chapman JR, et al. Anal Chem. 2023 Dec 19;95(50):18316-18325. doi: 10.1021/acs.analchem.3c02319. Epub 2023 Dec 4. Anal Chem. 2023. PMID: 38049117 Free article.

3

Secreted frizzled related-protein 2 is prognostic for human pancreatic cancer patient survival and is associated with fibrosis.

Siegel JB, Nasarre P, Hsu L, Mukherjee R, Gormley M, Richardson B, Khan I, Morningstar JE, Hilliard E, O'Bryan JP, Helke KL, Spruill L, Dolloff NG, Klauber-DeMore N. Siegel JB, et al. Cancer Biomark. 2023;38(3):287-300. doi: 10.3233/CBM-220044. Cancer Biomark. 2023. PMID: 37955079 Free PMC article.

4

Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.

Akkapeddi P, Hattori T, Khan I, Glasser E, Koide A, Ketavarapu G, Whaby M, Zuberi M, Teng KW, Lefler J, Maso L, Bang I, Ostrowski MC, O'Bryan JP, Koide S. Akkapeddi P, et al. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2302485120. doi: 10.1073/pnas.2302485120. Epub 2023 Jul 3. Proc Natl Acad Sci U S A. 2023. PMID: 37399416 Free PMC article.

5

Monobody Inhibitor Selective to the Phosphatase Domain of SHP2 and its Use as a Probe for Quantifying SHP2 Allosteric Regulation.

Sha F, Kurosawa K, Glasser E, Ketavarapu G, Albazzaz S, Koide A, Koide S. Sha F, et al. J Mol Biol. 2023 Apr 15;435(8):168010. doi: 10.1016/j.jmb.2023.168010. Epub 2023 Feb 16. J Mol Biol. 2023. PMID: 36806475 Free PMC article.

6

Mutations in the α4-α5 allosteric lobe of RAS do not significantly impair RAS signaling or self-association.

Whaby M, Wallon L, Mazzei M, Khan I, Teng KW, Koide S, O'Bryan JP. Whaby M, et al. J Biol Chem. 2022 Dec;298(12):102661. doi: 10.1016/j.jbc.2022.102661. Epub 2022 Nov 9. J Biol Chem. 2022. PMID: 36334633 Free PMC article.

7

Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket.

Wallon L, Khan I, Teng KW, Koide A, Zuberi M, Li J, Ketavarapu G, Traaseth NJ, O'Bryan JP, Koide S. Wallon L, et al. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2204481119. doi: 10.1073/pnas.2204481119. Epub 2022 Oct 17. Proc Natl Acad Sci U S A. 2022. PMID: 36252024 Free PMC article.

8

Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants.

Khan I, Koide A, Zuberi M, Ketavarapu G, Denbaum E, Teng KW, Rhett JM, Spencer-Smith R, Hobbs GA, Camp ER, Koide S, O'Bryan JP. Khan I, et al. Cell Rep. 2022 Feb 8;38(6):110322. doi: 10.1016/j.celrep.2022.110322. Cell Rep. 2022. PMID: 35139380 Free PMC article.

9

Targeting the "undruggable" RAS with biologics.

Whaby M, Khan I, O'Bryan JP. Whaby M, et al. Adv Cancer Res. 2022;153:237-266. doi: 10.1016/bs.acr.2021.07.006. Epub 2021 Aug 13. Adv Cancer Res. 2022. PMID: 35101232 Free PMC article. Review.

10

High-valency Anti-CD99 Antibodies Toward the Treatment of T Cell Acute Lymphoblastic Leukemia.

Romero LA, Hattori T, Ali MAE, Ketavarapu G, Koide A, Park CY, Koide S. Romero LA, et al. J Mol Biol. 2022 Mar 15;434(5):167402. doi: 10.1016/j.jmb.2021.167402. Epub 2021 Dec 24. J Mol Biol. 2022. PMID: 34958778 Free PMC article.

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