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Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Cichocki F, Bjordahl R, Goodridge JP, Mahmood S, Gaidarova S, Abujarour R, Davis ZB, Merino A, Tuininga K, Wang H, Kumar A, Groff B, Witty A, Bonello G, Huffman J, Dailey T, Lee TT, Malmberg KJ, Walcheck B, Höpken U, Rehm A, Valamehr B, Miller JS. Cichocki F, et al. Nat Commun. 2022 Nov 29;13(1):7341. doi: 10.1038/s41467-022-35127-2. Nat Commun. 2022. PMID: 36446823 Free PMC article.
Dual antigen-targeted off-the-shelf NK cells show durable response and prevent antigen escape in lymphoma and leukemia.
Cichocki F, Goodridge JP, Bjordahl R, Mahmood S, Davis ZB, Gaidarova S, Abujarour R, Groff B, Witty A, Wang H, Tuininga K, Kodal B, Felices M, Bonello G, Huffman J, Dailey T, Lee TT, Walcheck B, Valamehr B, Miller JS. Cichocki F, et al. Blood. 2022 Dec 8;140(23):2451-2462. doi: 10.1182/blood.2021015184. Blood. 2022. PMID: 35917442 Free PMC article.
Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy.
Woan KV, Kim H, Bjordahl R, Davis ZB, Gaidarova S, Goulding J, Hancock B, Mahmood S, Abujarour R, Wang H, Tuininga K, Zhang B, Wu CY, Kodal B, Khaw M, Bendzick L, Rogers P, Ge MQ, Bonello G, Meza M, Felices M, Huffman J, Dailey T, Lee TT, Walcheck B, Malmberg KJ, Blazar BR, Bryceson YT, Valamehr B, Miller JS, Cichocki F. Woan KV, et al. Cell Stem Cell. 2021 Dec 2;28(12):2062-2075.e5. doi: 10.1016/j.stem.2021.08.013. Epub 2021 Sep 14. Cell Stem Cell. 2021. PMID: 34525347 Free PMC article.
27 results