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Page 1
PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic Leukemia.
Li J, Hlavka-Zhang J, Shrimp JH, Piper C, Dupéré-Richér D, Roth JS, Jing D, Casellas Román HL, Troche C, Swaroop A, Kulis M, Oyer JA, Will CM, Shen M, Riva A, Bennett RL, Ferrando AA, Hall MD, Lock RB, Licht JD. Li J, et al. Cancer Discov. 2022 Jan;12(1):186-203. doi: 10.1158/2159-8290.CD-20-1771. Epub 2021 Aug 20. Cancer Discov. 2022. PMID: 34417224
Targeting epigenetic mechanisms to overcome venetoclax resistance.
Prado G, Kaestner CL, Licht JD, Bennett RL. Prado G, et al. Biochim Biophys Acta Mol Cell Res. 2021 Jul;1868(8):119047. doi: 10.1016/j.bbamcr.2021.119047. Epub 2021 May 1. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33945824 Free PMC article. Review.
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.
Yusufova N, Kloetgen A, Teater M, Osunsade A, Camarillo JM, Chin CR, Doane AS, Venters BJ, Portillo-Ledesma S, Conway J, Phillip JM, Elemento O, Scott DW, Béguelin W, Licht JD, Kelleher NL, Staudt LM, Skoultchi AI, Keogh MC, Apostolou E, Mason CE, Imielinski M, Schlick T, David Y, Tsirigos A, Allis CD, Soshnev AA, Cesarman E, Melnick AM. Yusufova N, et al. Nature. 2021 Jan;589(7841):299-305. doi: 10.1038/s41586-020-3017-y. Epub 2020 Dec 9. Nature. 2021. PMID: 33299181 Free PMC article.
15 results