R01 CA178627/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2013	2
2014	3
2015	10
2016	3
2017	5
2018	4
2019	6
2020	2
2021	6
2022	1
2024	0

1

Kras^G12D induces changes in chromatin territories that differentially impact early nuclear reprogramming in pancreatic cells.

Mathison AJ, Kerketta R, de Assuncao TM, Leverence E, Zeighami A, Urrutia G, Stodola TJ, di Magliano MP, Iovanna JL, Zimmermann MT, Lomberk G, Urrutia R. Mathison AJ, et al. Genome Biol. 2021 Oct 14;22(1):289. doi: 10.1186/s13059-021-02498-6. Genome Biol. 2021. PMID: 34649604 Free PMC article.

2

Inactivation of the Euchromatic Histone-Lysine N-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks.

Urrutia G, de Assuncao TM, Mathison AJ, Salmonson A, Kerketta R, Zeighami A, Stodola TJ, Adsay V, Pehlivanoglu B, Dwinell MB, Zimmermann MT, Iovanna JL, Urrutia R, Lomberk G. Urrutia G, et al. Front Cell Dev Biol. 2021 Jun 23;9:681153. doi: 10.3389/fcell.2021.681153. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34249932 Free PMC article.

3

Metabolomic profiling of pancreatic adenocarcinoma reveals key features driving clinical outcome and drug resistance.

Kaoutari AE, Fraunhoffer NA, Hoare O, Teyssedou C, Soubeyran P, Gayet O, Roques J, Lomberk G, Urrutia R, Dusetti N, Iovanna J. Kaoutari AE, et al. EBioMedicine. 2021 Apr;66:103332. doi: 10.1016/j.ebiom.2021.103332. Epub 2021 Apr 13. EBioMedicine. 2021. PMID: 33862584 Free PMC article.

4

A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer.

Kloesch B, Ionasz V, Paliwal S, Hruschka N, Martinez de Villarreal J, Öllinger R, Mueller S, Dienes HP, Schindl M, Gruber ES, Stift J, Herndler-Brandstetter D, Lomberk GA, Seidler B, Saur D, Rad R, Urrutia RA, Real FX, Martinelli P. Kloesch B, et al. Gut. 2022 Apr;71(4):766-777. doi: 10.1136/gutjnl-2020-321397. Epub 2021 Apr 12. Gut. 2022. PMID: 33846140 Free PMC article.

5

Interpreting Sequence Variation in PDAC-Predisposing Genes Using a Multi-Tier Annotation Approach Performed at the Gene, Patient, and Cohort Level.

Zimmermann MT, Mathison AJ, Stodola T, Evans DB, Abrudan JL, Demos W, Tschannen M, Aldakkak M, Geurts J, Lomberk G, Tsai S, Urrutia R. Zimmermann MT, et al. Front Oncol. 2021 Mar 5;11:606820. doi: 10.3389/fonc.2021.606820. eCollection 2021. Front Oncol. 2021. PMID: 33747920 Free PMC article.

6

Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction.

Chi YI, Stodola TJ, De Assuncao TM, Leverence EN, Tripathi S, Dsouza NR, Mathison AJ, Basel DG, Volkman BF, Smith BC, Lomberk G, Zimmermann MT, Urrutia R. Chi YI, et al. Orphanet J Rare Dis. 2021 Feb 5;16(1):66. doi: 10.1186/s13023-021-01692-w. Orphanet J Rare Dis. 2021. PMID: 33546721 Free PMC article.

7

Discovery, expression, cellular localization, and molecular properties of a novel, alternative spliced HP1γ isoform, lacking the chromoshadow domain.

Mathison A, Milech De Assuncao T, Dsouza NR, Williams M, Zimmermann MT, Urrutia R, Lomberk G. Mathison A, et al. PLoS One. 2020 Feb 6;15(2):e0217452. doi: 10.1371/journal.pone.0217452. eCollection 2020. PLoS One. 2020. PMID: 32027651 Free PMC article.

8

Combined Targeting of G9a and Checkpoint Kinase 1 Synergistically Inhibits Pancreatic Cancer Cell Growth by Replication Fork Collapse.

Urrutia G, Salmonson A, Toro-Zapata J, de Assuncao TM, Mathison A, Dusetti N, Iovanna J, Urrutia R, Lomberk G. Urrutia G, et al. Mol Cancer Res. 2020 Mar;18(3):448-462. doi: 10.1158/1541-7786.MCR-19-0490. Epub 2019 Dec 10. Mol Cancer Res. 2020. PMID: 31822519 Free PMC article.

9

Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma.

Santofimia-Castaño P, Xia Y, Peng L, Velázquez-Campoy A, Abián O, Lan W, Lomberk G, Urrutia R, Rizzuti B, Soubeyran P, Neira JL, Iovanna J. Santofimia-Castaño P, et al. Cells. 2019 Nov 17;8(11):1453. doi: 10.3390/cells8111453. Cells. 2019. PMID: 31744261 Free PMC article. Review.

10

Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine.

Lomberk G, Dusetti N, Iovanna J, Urrutia R. Lomberk G, et al. Nat Commun. 2019 Aug 28;10(1):3875. doi: 10.1038/s41467-019-11812-7. Nat Commun. 2019. PMID: 31462645 Free PMC article. Review.

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