R01 CA172379/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2014	5
2015	7
2016	7
2017	4
2018	4
2019	4
2020	2
2021	2
2022	1
2024	0

1

Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 Inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells.

Guo L, Zhang W, Xie Y, Chen X, Olmstead EE, Lian M, Zhang B, Zaytseva YY, Evers BM, Spielmann HP, Liu X, Watt DS, Liu C. Guo L, et al. Mol Cancer Ther. 2022 May 4;21(5):740-750. doi: 10.1158/1535-7163.MCT-21-0925. Mol Cancer Ther. 2022. PMID: 35247917 Free PMC article.

2

Potent Synergistic Effect on C-Myc-Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor.

Xie Y, Zhang W, Guo L, Kril LM, Begley KL, Sviripa VM, Chen X, Liu X, Lee EY, He D, Wang C, Gao T, Liu X, Evers BM, Watt DS, Liu C. Xie Y, et al. Mol Cancer Ther. 2021 Oct;20(10):1893-1903. doi: 10.1158/1535-7163.MCT-20-1017. Epub 2021 Aug 10. Mol Cancer Ther. 2021. PMID: 34376582 Free PMC article.

3

Pictet-Spengler condensations using 4-(2-aminoethyl)coumarins.

Sviripa VM, Fiandalo MV, Begley KL, Wyrebek P, Kril LM, Balia AG, Parkin SR, Subramanian V, Chen X, Williams AH, Zhan CG, Liu C, Mohler JL, Watt DS. Sviripa VM, et al. New J Chem. 2020 Aug 21;44(31):13415-13429. doi: 10.1039/d0nj02664f. Epub 2020 Jul 22. New J Chem. 2020. PMID: 33795928 Free PMC article.

4

Broad-Spectrum Antifungal Agents: Fluorinated Aryl- and Heteroaryl-Substituted Hydrazones.

Thamban Chandrika N, Dennis EK, Brubaker KR, Kwiatkowski S, Watt DS, Garneau-Tsodikova S. Thamban Chandrika N, et al. ChemMedChem. 2021 Jan 8;16(1):124-133. doi: 10.1002/cmdc.202000626. Epub 2020 Oct 16. ChemMedChem. 2021. PMID: 33063957 Free PMC article.

5

An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors.

Zhang W, Sviripa VM, Kril LM, Yu T, Xie Y, Hubbard WB, Sullivan PG, Chen X, Zhan CG, Yang-Hartwich Y, Evers BM, Spear BT, Gedaly R, Watt DS, Liu C. Zhang W, et al. J Med Chem. 2019 Dec 26;62(24):11348-11358. doi: 10.1021/acs.jmedchem.9b01685. Epub 2019 Dec 16. J Med Chem. 2019. PMID: 31774672 Free PMC article.

6

Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation.

Sinner HF, Johnson J, Rychahou PG, Watt DS, Zaytseva YY, Liu C, Evers BM. Sinner HF, et al. PLoS One. 2019 Oct 24;14(10):e0224253. doi: 10.1371/journal.pone.0224253. eCollection 2019. PLoS One. 2019. PMID: 31648230 Free PMC article.

7

Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish.

Xie Y, Kril LM, Yu T, Zhang W, Frasinyuk MS, Bondarenko SP, Kondratyuk KM, Hausman E, Martin ZM, Wyrebek PP, Liu X, Deaciuc A, Dwoskin LP, Chen J, Zhu H, Zhan CG, Sviripa VM, Blackburn J, Watt DS, Liu C. Xie Y, et al. Sci Rep. 2019 Apr 23;9(1):6439. doi: 10.1038/s41598-019-42917-0. Sci Rep. 2019. PMID: 31015569 Free PMC article.

8

N,N'-diaryl-bishydrazones in a biphenyl platform: Broad spectrum antifungal agents.

Thamban Chandrika N, Dennis EK, Shrestha SK, Ngo HX, Green KD, Kwiatkowski S, Deaciuc AG, Dwoskin LP, Watt DS, Garneau-Tsodikova S. Thamban Chandrika N, et al. Eur J Med Chem. 2019 Feb 15;164:273-281. doi: 10.1016/j.ejmech.2018.12.042. Epub 2018 Dec 18. Eur J Med Chem. 2019. PMID: 30597328 Free PMC article.

9

Efficient Synthesis of Aurone Mannich Bases and Evaluation of their Antineoplastic Activity in PC-3 Prostate Cancer Cells.

Popova AV, Frasinyuk MS, Bondarenko SP, Zhang W, Xie Y, Martin ZM, Cai X, Fiandalo MV, Mohler JL, Liu C, Watt DS, Sviripa VM. Popova AV, et al. Chem Zvesti. 2018 Oct;72(10):2443-2456. doi: 10.1007/s11696-018-0485-8. Epub 2018 Apr 28. Chem Zvesti. 2018. PMID: 36238867 Free PMC article.

10

Deptor Is a Novel Target of Wnt/β-Catenin/c-Myc and Contributes to Colorectal Cancer Cell Growth.

Wang Q, Zhou Y, Rychahou P, Harris JW, Zaytseva YY, Liu J, Wang C, Weiss HL, Liu C, Lee EY, Evers BM. Wang Q, et al. Cancer Res. 2018 Jun 15;78(12):3163-3175. doi: 10.1158/0008-5472.CAN-17-3107. Epub 2018 Apr 17. Cancer Res. 2018. PMID: 29666061 Free PMC article.

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