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Crystal structure of 13-(E)-(2-amino-benzyl-idene)parthenolide.
Bommagani S, Penthala NR, Parkin S, Crooks PA. Bommagani S, et al. Acta Crystallogr E Crystallogr Commun. 2018 Oct 9;74(Pt 11):1543-1546. doi: 10.1107/S2056989018013622. eCollection 2018 Nov 1. Acta Crystallogr E Crystallogr Commun. 2018. PMID: 30443377 Free PMC article.
DMAPT inhibits NF-κB activity and increases sensitivity of prostate cancer cells to X-rays in vitro and in tumor xenografts in vivo.
Mendonca MS, Turchan WT, Alpuche ME, Watson CN, Estabrook NC, Chin-Sinex H, Shapiro JB, Imasuen-Williams IE, Rangel G, Gilley DP, Huda N, Crooks PA, Shapiro RH. Mendonca MS, et al. Free Radic Biol Med. 2017 Nov;112:318-326. doi: 10.1016/j.freeradbiomed.2017.08.001. Epub 2017 Aug 3. Free Radic Biol Med. 2017. PMID: 28782644 Free PMC article.
Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.
Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT. Pei S, et al. J Biol Chem. 2016 Oct 14;291(42):21984-22000. doi: 10.1074/jbc.M116.750653. Epub 2016 Aug 29. J Biol Chem. 2016. PMID: 27573247 Free PMC article.
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