R01 CA140575/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2011	2
2012	3
2013	5
2014	7
2015	3
2016	6
2017	5
2018	2
2020	1
2024	0

1

Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition.

Cai SF, Chu SH, Goldberg AD, Parvin S, Koche RP, Glass JL, Stein EM, Tallman MS, Sen F, Famulare CA, Cusan M, Huang CH, Chen CW, Zou L, Cordner KB, DelGaudio NL, Durani V, Kini M, Rex M, Tian HS, Zuber J, Baslan T, Lowe SW, Rienhoff HY Jr, Letai A, Levine RL, Armstrong SA. Cai SF, et al. Cancer Discov. 2020 Oct;10(10):1500-1513. doi: 10.1158/2159-8290.CD-19-1469. Epub 2020 Jun 30. Cancer Discov. 2020. PMID: 32606137 Free PMC article.

2

A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response.

Hoshii T, Cifani P, Feng Z, Huang CH, Koche R, Chen CW, Delaney CD, Lowe SW, Kentsis A, Armstrong SA. Hoshii T, et al. Cell. 2018 Feb 22;172(5):1007-1021.e17. doi: 10.1016/j.cell.2018.01.032. Cell. 2018. PMID: 29474905 Free PMC article.

3

LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML.

Cusan M, Cai SF, Mohammad HP, Krivtsov A, Chramiec A, Loizou E, Witkin MD, Smitheman KN, Tenen DG, Ye M, Will B, Steidl U, Kruger RG, Levine RL, Rienhoff HY Jr, Koche RP, Armstrong SA. Cusan M, et al. Blood. 2018 Apr 12;131(15):1730-1742. doi: 10.1182/blood-2017-09-807024. Epub 2018 Feb 16. Blood. 2018. PMID: 29453291 Free PMC article.

4

PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D.

Toska E, Osmanbeyoglu HU, Castel P, Chan C, Hendrickson RC, Elkabets M, Dickler MN, Scaltriti M, Leslie CS, Armstrong SA, Baselga J. Toska E, et al. Science. 2017 Mar 24;355(6331):1324-1330. doi: 10.1126/science.aah6893. Science. 2017. PMID: 28336670 Free PMC article.

5

Mixed-Lineage Leukemia Fusions and Chromatin in Leukemia.

Krivtsov AV, Hoshii T, Armstrong SA. Krivtsov AV, et al. Cold Spring Harb Perspect Med. 2017 Nov 1;7(11):a026658. doi: 10.1101/cshperspect.a026658. Cold Spring Harb Perspect Med. 2017. PMID: 28242784 Free PMC article. Review.

6

ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.

Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, Joseph JK, Wang X, Loh YE, Erb MA, Souza AL, Bradner JE, Shen L, Li W, Li H, Allis CD, Armstrong SA, Shi X. Wan L, et al. Nature. 2017 Mar 9;543(7644):265-269. doi: 10.1038/nature21687. Epub 2017 Mar 1. Nature. 2017. PMID: 28241141 Free PMC article.

7

Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis.

Valerio DG, Xu H, Chen CW, Hoshii T, Eisold ME, Delaney C, Cusan M, Deshpande AJ, Huang CH, Lujambio A, Zheng YG, Zuber J, Pandita TK, Lowe SW, Armstrong SA. Valerio DG, et al. Cancer Res. 2017 Apr 1;77(7):1753-1762. doi: 10.1158/0008-5472.CAN-16-2374. Epub 2017 Feb 15. Cancer Res. 2017. PMID: 28202522 Free PMC article.

8

NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.

Xu H, Valerio DG, Eisold ME, Sinha A, Koche RP, Hu W, Chen CW, Chu SH, Brien GL, Park CY, Hsieh JJ, Ernst P, Armstrong SA. Xu H, et al. Cancer Cell. 2016 Dec 12;30(6):863-878. doi: 10.1016/j.ccell.2016.10.019. Epub 2016 Nov 23. Cancer Cell. 2016. PMID: 27889185 Free PMC article.

9

Histone acetyltransferase activity of MOF is required for adult but not early fetal hematopoiesis in mice.

Valerio DG, Xu H, Eisold ME, Woolthuis CM, Pandita TK, Armstrong SA. Valerio DG, et al. Blood. 2017 Jan 5;129(1):48-59. doi: 10.1182/blood-2016-05-714568. Epub 2016 Nov 8. Blood. 2017. PMID: 27827827 Free PMC article.

10

Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia.

Kühn MW, Song E, Feng Z, Sinha A, Chen CW, Deshpande AJ, Cusan M, Farnoud N, Mupo A, Grove C, Koche R, Bradner JE, de Stanchina E, Vassiliou GS, Hoshii T, Armstrong SA. Kühn MW, et al. Cancer Discov. 2016 Oct;6(10):1166-1181. doi: 10.1158/2159-8290.CD-16-0237. Epub 2016 Aug 17. Cancer Discov. 2016. PMID: 27535106 Free PMC article.

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