R01 CA039416/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 CA039416/CA/NCI NIH HHS/United States[Grants - PubMed

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Year	Number of Results
2000	1
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2008	5
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2011	5
2012	4
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2018	1
2024	0

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Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo.

Wible RS, Tran QT, Fathima S, Sutter CH, Kensler TW, Sutter TR. Wible RS, et al. Mol Pharmacol. 2018 Apr;93(4):297-308. doi: 10.1124/mol.117.110262. Epub 2018 Jan 24. Mol Pharmacol. 2018. PMID: 29367259 Free PMC article.

Genetic or pharmacologic activation of Nrf2 signaling fails to protect against aflatoxin genotoxicity in hypersensitive GSTA3 knockout mice.

Kensler KH, Slocum SL, Chartoumpekis DV, Dolan PM, Johnson NM, Ilic Z, Crawford DR, Sell S, Groopman JD, Kensler TW, Egner PA. Kensler KH, et al. Toxicol Sci. 2014 Jun;139(2):293-300. doi: 10.1093/toxsci/kfu056. Epub 2014 Mar 27. Toxicol Sci. 2014. PMID: 24675090 Free PMC article.

Complete protection against aflatoxin B(1)-induced liver cancer with a triterpenoid: DNA adduct dosimetry, molecular signature, and genotoxicity threshold.

Johnson NM, Egner PA, Baxter VK, Sporn MB, Wible RS, Sutter TR, Groopman JD, Kensler TW, Roebuck BD. Johnson NM, et al. Cancer Prev Res (Phila). 2014 Jul;7(7):658-65. doi: 10.1158/1940-6207.CAPR-13-0430. Epub 2014 Mar 24. Cancer Prev Res (Phila). 2014. PMID: 24662598 Free PMC article.

Keap1-nrf2 signaling: a target for cancer prevention by sulforaphane.

Kensler TW, Egner PA, Agyeman AS, Visvanathan K, Groopman JD, Chen JG, Chen TY, Fahey JW, Talalay P. Kensler TW, et al. Top Curr Chem. 2013;329:163-77. doi: 10.1007/128_2012_339. Top Curr Chem. 2013. PMID: 22752583 Free PMC article. Review.

Validation of the multiple sensor mechanism of the Keap1-Nrf2 system.

Takaya K, Suzuki T, Motohashi H, Onodera K, Satomi S, Kensler TW, Yamamoto M. Takaya K, et al. Free Radic Biol Med. 2012 Aug 15;53(4):817-27. doi: 10.1016/j.freeradbiomed.2012.06.023. Epub 2012 Jun 23. Free Radic Biol Med. 2012. PMID: 22732183 Free PMC article.

Lactone metabolite common to the carcinogens dioxane, diethylene glycol, and N-nitrosomorpholine: aqueous chemistry and failure to mediate liver carcinogenesis in the F344 rat.

Koissi N, Shah NH, Ginevan B, Eck WS, Roebuck BD, Fishbein JC. Koissi N, et al. Chem Res Toxicol. 2012 May 21;25(5):1022-8. doi: 10.1021/tx3000076. Epub 2012 Apr 12. Chem Res Toxicol. 2012. PMID: 22458541 Free PMC article.

Notes from the field: "green" chemoprevention as frugal medicine.

Fahey JW, Talalay P, Kensler TW. Fahey JW, et al. Cancer Prev Res (Phila). 2012 Feb;5(2):179-88. doi: 10.1158/1940-6207.CAPR-11-0572. Cancer Prev Res (Phila). 2012. PMID: 22307565 Free PMC article. Review.

Aldo-keto reductase-7A protects liver cells and tissues from acetaminophen-induced oxidative stress and hepatotoxicity.

Ahmed MM, Wang T, Luo Y, Ye S, Wu Q, Guo Z, Roebuck BD, Sutter TR, Yang JY. Ahmed MM, et al. Hepatology. 2011 Oct;54(4):1322-32. doi: 10.1002/hep.24493. Epub 2011 Sep 6. Hepatology. 2011. PMID: 21688283

Present and future directions of translational research on aflatoxin and hepatocellular carcinoma. A review.

Wogan GN, Kensler TW, Groopman JD. Wogan GN, et al. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012;29(2):249-57. doi: 10.1080/19440049.2011.563370. Epub 2011 Jun 1. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012. PMID: 21623489 Free PMC article. Review.

Nrf2: control of sensitivity to carcinogens.

Slocum SL, Kensler TW. Slocum SL, et al. Arch Toxicol. 2011 Apr;85(4):273-84. doi: 10.1007/s00204-011-0675-4. Epub 2011 Mar 3. Arch Toxicol. 2011. PMID: 21369766 Review.

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