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Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site.
van Vliet VJE, Huynh N, Palà J, Patel A, Singer A, Slater C, Chung J, van Huizen M, Teyra J, Miersch S, Luu GK, Ye W, Sharma N, Ganaie SS, Russell R, Chen C, Maynard M, Amarasinghe GK, Mark BL, Kikkert M, Sidhu SS. van Vliet VJE, et al. PLoS Pathog. 2022 Dec 22;18(12):e1011065. doi: 10.1371/journal.ppat.1011065. eCollection 2022 Dec. PLoS Pathog. 2022. PMID: 36548304 Free PMC article.
Monoclonal antibodies binding data for SARS-CoV-2 proteins.
Mishra N, Teyra J, Boytz R, Miersch S, Merritt TN, Cardarelli L, Gorelik M, Mihalic F, Jemth P, Davey RA, Sidhu SS, Leung DW, Amarasinghe GK. Mishra N, et al. Data Brief. 2022 Aug;43:108415. doi: 10.1016/j.dib.2022.108415. Epub 2022 Jun 24. Data Brief. 2022. PMID: 35789908 Free PMC article.
Rapid detection of an Ebola biomarker with optical microring resonators.
Qavi AJ, Meserve K, Aman MJ, Vu H, Zeitlin L, Dye JM, Froude JW, Leung DW, Yang L, Holtsberg FW, Bailey RC, Amarasinghe GK. Qavi AJ, et al. Cell Rep Methods. 2022 Jun 8;2(6):100234. doi: 10.1016/j.crmeth.2022.100234. eCollection 2022 Jun 20. Cell Rep Methods. 2022. PMID: 35784644 Free PMC article.
A cryptic pocket in Ebola VP35 allosterically controls RNA binding.
Cruz MA, Frederick TE, Mallimadugula UL, Singh S, Vithani N, Zimmerman MI, Porter JR, Moeder KE, Amarasinghe GK, Bowman GR. Cruz MA, et al. Nat Commun. 2022 Apr 27;13(1):2269. doi: 10.1038/s41467-022-29927-9. Nat Commun. 2022. PMID: 35477718 Free PMC article.
37 results