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HLA variants have different preferences to present proteins with specific molecular functions which are complemented in frequent haplotypes.
Karnaukhov V, Paes W, Woodhouse IB, Partridge T, Nicastri A, Brackenridge S, Shcherbinin D, Chudakov DM, Zvyagin IV, Ternette N, Koohy H, Borrow P, Shugay M. Karnaukhov V, et al. Front Immunol. 2022 Dec 20;13:1067463. doi: 10.3389/fimmu.2022.1067463. eCollection 2022. Front Immunol. 2022. PMID: 36605212 Free PMC article.
Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART.
Obregon-Perko V, Bricker KM, Mensah G, Uddin F, Rotolo L, Vanover D, Desai Y, Santangelo PJ, Jean S, Wood JS, Connor-Stroud FC, Ehnert S, Berendam SJ, Liang S, Vanderford TH, Bar KJ, Shaw GM, Silvestri G, Kumar A, Fouda GG, Permar SR, Chahroudi A. Obregon-Perko V, et al. JCI Insight. 2021 Dec 8;6(23):e152526. doi: 10.1172/jci.insight.152526. JCI Insight. 2021. PMID: 34699383 Free PMC article.
New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure.
Li H, Wang S, Lee FH, Roark RS, Murphy AI, Smith J, Zhao C, Rando J, Chohan N, Ding Y, Kim E, Lindemuth E, Bar KJ, Pandrea I, Apetrei C, Keele BF, Lifson JD, Lewis MG, Denny TN, Haynes BF, Hahn BH, Shaw GM. Li H, et al. J Virol. 2021 May 10;95(11):e00071-21. doi: 10.1128/JVI.00071-21. Epub 2021 Mar 3. J Virol. 2021. PMID: 33658341 Free PMC article.
Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption.
Gondim MVP, Sherrill-Mix S, Bibollet-Ruche F, Russell RM, Trimboli S, Smith AG, Li Y, Liu W, Avitto AN, DeVoto JC, Connell J, Fenton-May AE, Pellegrino P, Williams I, Papasavvas E, Lorenzi JCC, Salantes DB, Mampe F, Monroy MA, Cohen YZ, Heath S, Saag MS, Montaner LJ, Collman RG, Siliciano JM, Siliciano RF, Plenderleith LJ, Sharp PM, Caskey M, Nussenzweig MC, Shaw GM, Borrow P, Bar KJ, Hahn BH. Gondim MVP, et al. Sci Transl Med. 2021 Jan 13;13(576):eabd8179. doi: 10.1126/scitranslmed.abd8179. Sci Transl Med. 2021. PMID: 33441429 Free PMC article.
Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4+ T Cells.
Obregon-Perko V, Bricker KM, Mensah G, Uddin F, Kumar MR, Fray EJ, Siliciano RF, Schoof N, Horner A, Mavigner M, Liang S, Vanderford T, Sass J, Chan C, Berendam SJ, Bar KJ, Shaw GM, Silvestri G, Fouda GG, Permar SR, Chahroudi A. Obregon-Perko V, et al. J Virol. 2020 Dec 22;95(2):e01669-20. doi: 10.1128/JVI.01669-20. Print 2020 Dec 22. J Virol. 2020. PMID: 33087463 Free PMC article.
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