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Page 1
Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Tetreau G, Banneville AS, Andreeva EA, Brewster AS, Hunter MS, Sierra RG, Teulon JM, Young ID, Burke N, Grünewald TA, Beaudouin J, Snigireva I, Fernandez-Luna MT, Burt A, Park HW, Signor L, Bafna JA, Sadir R, Fenel D, Boeri-Erba E, Bacia M, Zala N, Laporte F, Després L, Weik M, Boutet S, Rosenthal M, Coquelle N, Burghammer M, Cascio D, Sawaya MR, Winterhalter M, Gratton E, Gutsche I, Federici B, Pellequer JL, Sauter NK, Colletier JP. Tetreau G, et al. Nat Commun. 2020 Mar 2;11(1):1153. doi: 10.1038/s41467-020-14894-w. Nat Commun. 2020. PMID: 32123169 Free PMC article.
De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure.
Colletier JP, Sawaya MR, Gingery M, Rodriguez JA, Cascio D, Brewster AS, Michels-Clark T, Hice RH, Coquelle N, Boutet S, Williams GJ, Messerschmidt M, DePonte DP, Sierra RG, Laksmono H, Koglin JE, Hunter MS, Park HW, Uervirojnangkoorn M, Bideshi DK, Brunger AT, Federici BA, Sauter NK, Eisenberg DS. Colletier JP, et al. Nature. 2016 Nov 3;539(7627):43-47. doi: 10.1038/nature19825. Epub 2016 Sep 28. Nature. 2016. PMID: 27680699 Free PMC article.
Protein crystal structure obtained at 2.9 Å resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Sawaya MR, Cascio D, Gingery M, Rodriguez J, Goldschmidt L, Colletier JP, Messerschmidt MM, Boutet S, Koglin JE, Williams GJ, Brewster AS, Nass K, Hattne J, Botha S, Doak RB, Shoeman RL, DePonte DP, Park HW, Federici BA, Sauter NK, Schlichting I, Eisenberg DS. Sawaya MR, et al. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12769-74. doi: 10.1073/pnas.1413456111. Epub 2014 Aug 18. Proc Natl Acad Sci U S A. 2014. PMID: 25136092 Free PMC article.
19 results