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Year Number of Results
2020 2
2021 6
2022 1
2023 1
2024 0

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Page 1
Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy.
Chella Krishnan K, El Hachem EJ, Keller MP, Patel SG, Carroll L, Vegas AD, Gerdes Gyuricza I, Light C, Cao Y, Pan C, Kaczor-Urbanowicz KE, Shravah V, Anum D, Pellegrini M, Lee CF, Seldin MM, Rosenthal NA, Churchill GA, Attie AD, Parker B, James DE, Lusis AJ. Chella Krishnan K, et al. Elife. 2023 Jun 5;12:e82619. doi: 10.7554/eLife.82619. Elife. 2023. PMID: 37276142 Free PMC article.
Sex differences in heart mitochondria regulate diastolic dysfunction.
Cao Y, Vergnes L, Wang YC, Pan C, Chella Krishnan K, Moore TM, Rosa-Garrido M, Kimball TH, Zhou Z, Charugundla S, Rau CD, Seldin MM, Wang J, Wang Y, Vondriska TM, Reue K, Lusis AJ. Cao Y, et al. Nat Commun. 2022 Jul 4;13(1):3850. doi: 10.1038/s41467-022-31544-5. Nat Commun. 2022. PMID: 35787630 Free PMC article.
Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2.
Chella Krishnan K, Vergnes L, Acín-Pérez R, Stiles L, Shum M, Ma L, Mouisel E, Pan C, Moore TM, Péterfy M, Romanoski CE, Reue K, Björkegren JLM, Laakso M, Liesa M, Lusis AJ. Chella Krishnan K, et al. Nat Metab. 2021 Nov;3(11):1552-1568. doi: 10.1038/s42255-021-00481-w. Epub 2021 Oct 25. Nat Metab. 2021. PMID: 34697471 Free PMC article.
Recruitment and remodeling of peridroplet mitochondria in human adipose tissue.
Acín-Perez R, Petcherski A, Veliova M, Benador IY, Assali EA, Colleluori G, Cinti S, Brownstein AJ, Baghdasarian S, Livhits MJ, Yeh MW, Krishnan KC, Vergnes L, Winn NC, Padilla J, Liesa M, Sacks HS, Shirihai OS. Acín-Perez R, et al. Redox Biol. 2021 Oct;46:102087. doi: 10.1016/j.redox.2021.102087. Epub 2021 Jul 30. Redox Biol. 2021. PMID: 34411987 Free PMC article.
ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity.
Shum M, Shintre CA, Althoff T, Gutierrez V, Segawa M, Saxberg AD, Martinez M, Adamson R, Young MR, Faust B, Gharakhanian R, Su S, Chella Krishnan K, Mahdaviani K, Veliova M, Wolf DM, Ngo J, Nocito L, Stiles L, Abramson J, Lusis AJ, Hevener AL, Zoghbi ME, Carpenter EP, Liesa M. Shum M, et al. Sci Transl Med. 2021 May 19;13(594):eabd1869. doi: 10.1126/scitranslmed.abd1869. Sci Transl Med. 2021. PMID: 34011630 Free PMC article.
Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle.
Ferrara PJ, Rong X, Maschek JA, Verkerke AR, Siripoksup P, Song H, Green TD, Krishnan KC, Johnson JM, Turk J, Houmard JA, Lusis AJ, Drummond MJ, McClung JM, Cox JE, Shaikh SR, Tontonoz P, Holland WL, Funai K. Ferrara PJ, et al. J Clin Invest. 2021 Apr 15;131(8):e135963. doi: 10.1172/JCI135963. J Clin Invest. 2021. PMID: 33591957 Free PMC article.
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity.
Acín-Pérez R, Iborra S, Martí-Mateos Y, Cook ECL, Conde-Garrosa R, Petcherski A, Muñoz MDM, Martínez de Mena R, Krishnan KC, Jiménez C, Bolaños JP, Laakso M, Lusis AJ, Shirihai OS, Sancho D, Enríquez JA. Acín-Pérez R, et al. Nat Metab. 2020 Sep;2(9):974-988. doi: 10.1038/s42255-020-00273-8. Epub 2020 Sep 17. Nat Metab. 2020. PMID: 32943786 Free PMC article.
Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner.
Chella Krishnan K, Floyd RR, Sabir S, Jayasekera DW, Leon-Mimila PV, Jones AE, Cortez AA, Shravah V, Péterfy M, Stiles L, Canizales-Quinteros S, Divakaruni AS, Huertas-Vazquez A, Lusis AJ. Chella Krishnan K, et al. Cell Mol Gastroenterol Hepatol. 2021;11(2):389-406. doi: 10.1016/j.jcmgh.2020.09.004. Epub 2020 Sep 14. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32942044 Free PMC article.