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2019 2
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Page 1
Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.
Jain SU, Khazaei S, Marchione DM, Lundgren SM, Wang X, Weinberg DN, Deshmukh S, Juretic N, Lu C, Allis CD, Garcia BA, Jabado N, Lewis PW. Jain SU, et al. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27354-27364. doi: 10.1073/pnas.2006076117. Epub 2020 Oct 16. Proc Natl Acad Sci U S A. 2020. PMID: 33067396 Free PMC article.
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.
Weinberg DN, Papillon-Cavanagh S, Chen H, Yue Y, Chen X, Rajagopalan KN, Horth C, McGuire JT, Xu X, Nikbakht H, Lemiesz AE, Marchione DM, Marunde MR, Meiners MJ, Cheek MA, Keogh MC, Bareke E, Djedid A, Harutyunyan AS, Jabado N, Garcia BA, Li H, Allis CD, Majewski J, Lu C. Weinberg DN, et al. Nature. 2019 Sep;573(7773):281-286. doi: 10.1038/s41586-019-1534-3. Epub 2019 Sep 4. Nature. 2019. PMID: 31485078 Free PMC article.