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Bile salt hydrolase catalyses formation of amine-conjugated bile acids.
Rimal B, Collins SL, Tanes CE, Rocha ER, Granda MA, Solanki S, Hoque NJ, Gentry EC, Koo I, Reilly ER, Hao F, Paudel D, Singh V, Yan T, Kim MS, Bittinger K, Zackular JP, Krausz KW, Desai D, Amin S, Coleman JP, Shah YM, Bisanz JE, Gonzalez FJ, Vanden Heuvel JP, Wu GD, Zemel BS, Dorrestein PC, Weinert EE, Patterson AD. Rimal B, et al. Nature. 2024 Feb;626(8000):859-863. doi: 10.1038/s41586-023-06990-w. Epub 2024 Feb 7. Nature. 2024. PMID: 38326609 Free PMC article.
Roles of the gut microbiome in weight management.
Carmody RN, Bisanz JE. Carmody RN, et al. Nat Rev Microbiol. 2023 Aug;21(8):535-550. doi: 10.1038/s41579-023-00888-0. Epub 2023 May 3. Nat Rev Microbiol. 2023. PMID: 37138047 Review.
Making gut microbiomes from scratch.
Tian S, Bisanz JE. Tian S, et al. Cell Host Microbe. 2022 Nov 9;30(11):1508-1509. doi: 10.1016/j.chom.2022.10.005. Cell Host Microbe. 2022. PMID: 36356566 Free article.
Effects of caloric restriction on the gut microbiome are linked with immune senescence.
Sbierski-Kind J, Grenkowitz S, Schlickeiser S, Sandforth A, Friedrich M, Kunkel D, Glauben R, Brachs S, Mai K, Thürmer A, Radonić A, Drechsel O, Turnbaugh PJ, Bisanz JE, Volk HD, Spranger J, von Schwartzenberg RJ. Sbierski-Kind J, et al. Microbiome. 2022 Apr 4;10(1):57. doi: 10.1186/s40168-022-01249-4. Microbiome. 2022. PMID: 35379337 Free PMC article.
Human gut bacteria produce ΤΗ17-modulating bile acid metabolites.
Paik D, Yao L, Zhang Y, Bae S, D'Agostino GD, Zhang M, Kim E, Franzosa EA, Avila-Pacheco J, Bisanz JE, Rakowski CK, Vlamakis H, Xavier RJ, Turnbaugh PJ, Longman RS, Krout MR, Clish CB, Rastinejad F, Huttenhower C, Huh JR, Devlin AS. Paik D, et al. Nature. 2022 Mar;603(7903):907-912. doi: 10.1038/s41586-022-04480-z. Epub 2022 Mar 16. Nature. 2022. PMID: 35296854 Free PMC article.
Caloric restriction disrupts the microbiota and colonization resistance.
von Schwartzenberg RJ, Bisanz JE, Lyalina S, Spanogiannopoulos P, Ang QY, Cai J, Dickmann S, Friedrich M, Liu SY, Collins SL, Ingebrigtsen D, Miller S, Turnbaugh JA, Patterson AD, Pollard KS, Mai K, Spranger J, Turnbaugh PJ. von Schwartzenberg RJ, et al. Nature. 2021 Jul;595(7866):272-277. doi: 10.1038/s41586-021-03663-4. Epub 2021 Jun 23. Nature. 2021. PMID: 34163067 Free PMC article. Clinical Trial.