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2002 1
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2008 1
2009 2
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2012 4
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2014 2
2015 4
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2019 5
2020 4
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2024 2

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Page 1
Design and Synthesis of Novel N-Benzylidene Derivatives of 3-Amino-4-imino-3,5-dihydro-4H-chromeno[2,3-d]pyrimidine under Microwave, In Silico ADME Predictions, In Vitro Antitumoral Activities and In Vivo Toxicity.
Karoui S, Dhiabi M, Fakhfakh M, Abid S, Limanton E, Le Guével R, Charlier TD, Mainguy A, Mignen O, Paquin L, Ammar H, Bazureau JP. Karoui S, et al. Among authors: le guevel r. Pharmaceuticals (Basel). 2024 Apr 2;17(4):458. doi: 10.3390/ph17040458. Pharmaceuticals (Basel). 2024. PMID: 38675418 Free PMC article.
At the crossroads of fertility and metabolism: the importance of AMPK-dependent signaling in female infertility associated with hyperandrogenism.
Froment P, Plotton I, Giulivi C, Fabre S, Khoueiry R, Mourad NI, Horman S, Ramé C, Rouillon C, Grandhaye J, Bigot Y, Chevaleyre C, Le Guevel R, Mallegol P, Andriantsitohaina R, Guerif F, Tamburini J, Viollet B, Foretz M, Dupont J. Froment P, et al. Among authors: le guevel r. Hum Reprod. 2022 May 30;37(6):1207-1228. doi: 10.1093/humrep/deac067. Hum Reprod. 2022. PMID: 35459945 Free article.
Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A.
Bourahla K, Guihéneuf S, Limanton E, Paquin L, Le Guével R, Charlier T, Rahmouni M, Durieu E, Lozach O, Carreaux F, Meijer L, Bazureau JP. Bourahla K, et al. Among authors: le guevel r. Pharmaceuticals (Basel). 2021 Oct 27;14(11):1086. doi: 10.3390/ph14111086. Pharmaceuticals (Basel). 2021. PMID: 34832868 Free PMC article.
Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains.
Murthy AVR, Narendar V, Sampath Kumar N, Aparna P, Bhavani AKD, Solhi H, Le Guevel R, Roul J, Gautier F, Juin P, Reddy CR, Mosset P, Levoin N, Grée R. Murthy AVR, et al. Among authors: le guevel r. Bioorg Med Chem Lett. 2021 Nov 15;52:128390. doi: 10.1016/j.bmcl.2021.128390. Epub 2021 Sep 30. Bioorg Med Chem Lett. 2021. PMID: 34601029 Free article.
Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase.
Brahmaiah D, Kanaka Durga Bhavani A, Aparna P, Sampath Kumar N, Solhi H, Le Guevel R, Baratte B, Ruchaud S, Bach S, Singh Jadav S, Raji Reddy C, Roisnel T, Mosset P, Levoin N, Grée R. Brahmaiah D, et al. Among authors: le guevel r. Bioorg Med Chem. 2021 Feb 1;31:115962. doi: 10.1016/j.bmc.2020.115962. Epub 2020 Dec 31. Bioorg Med Chem. 2021. PMID: 33422908
43 results