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In vivo and in vitro degradation of heparan sulfate (HS) proteoglycans by HPR1 in pancreatic adenocarcinomas. Loss of cell surface HS suppresses fibroblast growth factor 2-mediated cell signaling and proliferation.
Xu X, Rao G, Quiros RM, Kim AW, Miao HQ, Brunn GJ, Platt JL, Gattuso P, Prinz RA. Xu X, et al. Among authors: quiros rm. J Biol Chem. 2007 Jan 26;282(4):2363-73. doi: 10.1074/jbc.M604218200. Epub 2006 Nov 22. J Biol Chem. 2007. PMID: 17121850 Free article.
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