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Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel J, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: quintana fj. bioRxiv [Preprint]. 2024 Jan 5:2024.01.04.574196. doi: 10.1101/2024.01.04.574196. bioRxiv. 2024. PMID: 38260616 Free PMC article. Updated. Preprint.
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation.
Mayo L, Trauger SA, Blain M, Nadeau M, Patel B, Alvarez JI, Mascanfroni ID, Yeste A, Kivisäkk P, Kallas K, Ellezam B, Bakshi R, Prat A, Antel JP, Weiner HL, Quintana FJ. Mayo L, et al. Among authors: quintana fj. Nat Med. 2014 Oct;20(10):1147-56. doi: 10.1038/nm.3681. Epub 2014 Sep 14. Nat Med. 2014. PMID: 25216636 Free PMC article.
Control of autoimmune CNS inflammation by astrocytes.
Rothhammer V, Quintana FJ. Rothhammer V, et al. Among authors: quintana fj. Semin Immunopathol. 2015 Nov;37(6):625-38. doi: 10.1007/s00281-015-0515-3. Epub 2015 Jul 30. Semin Immunopathol. 2015. PMID: 26223505 Free PMC article. Review.
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.
Rothhammer V, Mascanfroni ID, Bunse L, Takenaka MC, Kenison JE, Mayo L, Chao CC, Patel B, Yan R, Blain M, Alvarez JI, Kébir H, Anandasabapathy N, Izquierdo G, Jung S, Obholzer N, Pochet N, Clish CB, Prinz M, Prat A, Antel J, Quintana FJ. Rothhammer V, et al. Among authors: quintana fj. Nat Med. 2016 Jun;22(6):586-97. doi: 10.1038/nm.4106. Epub 2016 May 9. Nat Med. 2016. PMID: 27158906 Free PMC article.
Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation.
Rothhammer V, Kenison JE, Tjon E, Takenaka MC, de Lima KA, Borucki DM, Chao CC, Wilz A, Blain M, Healy L, Antel J, Quintana FJ. Rothhammer V, et al. Among authors: quintana fj. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2012-2017. doi: 10.1073/pnas.1615413114. Epub 2017 Feb 6. Proc Natl Acad Sci U S A. 2017. PMID: 28167760 Free PMC article.
Regulation of Astrocyte Functions in Multiple Sclerosis.
Wheeler MA, Quintana FJ. Wheeler MA, et al. Among authors: quintana fj. Cold Spring Harb Perspect Med. 2019 Jan 2;9(1):a029009. doi: 10.1101/cshperspect.a029009. Cold Spring Harb Perspect Med. 2019. PMID: 29358321 Free PMC article. Review.
Detection of aryl hydrocarbon receptor agonists in human samples.
Rothhammer V, Borucki DM, Kenison JE, Hewson P, Wang Z, Bakshi R, Sherr DH, Quintana FJ. Rothhammer V, et al. Among authors: quintana fj. Sci Rep. 2018 Mar 21;8(1):4970. doi: 10.1038/s41598-018-23323-4. Sci Rep. 2018. PMID: 29563571 Free PMC article.
225 results