Quadri LEN - Search Results

1

Transposon mutagenesis in Mycobacterium kansasii links a small RNA gene to colony morphology and biofilm formation and identifies 9,885 intragenic insertions that do not compromise colony outgrowth.

Budell WC, Germain GA, Janisch N, McKie-Krisberg Z, Jayaprakash AD, Resnick AE, Quadri LEN. Budell WC, et al. Among authors: quadri len. Microbiologyopen. 2020 Apr;9(4):e988. doi: 10.1002/mbo3.988. Epub 2020 Feb 21. Microbiologyopen. 2020. PMID: 32083796 Free PMC article.

2

Pleiotropic consequences of gene knockouts in the phthiocerol dimycocerosate and phenolic glycolipid biosynthetic gene cluster of the opportunistic human pathogen Mycobacterium marinum.

Mohandas P, Budell WC, Mueller E, Au A, Bythrow GV, Quadri LE. Mohandas P, et al. FEMS Microbiol Lett. 2016 Mar;363(5):fnw016. doi: 10.1093/femsle/fnw016. Epub 2016 Jan 26. FEMS Microbiol Lett. 2016. PMID: 26818253 Free PMC article.

3

Mycobacteria Encode Active and Inactive Classes of TesB Fatty-Acyl CoA Thioesterases Revealed through Structural and Functional Analysis.

Swarbrick CM, Bythrow GV, Aragao D, Germain GA, Quadri LE, Forwood JK. Swarbrick CM, et al. Biochemistry. 2017 Mar 14;56(10):1460-1472. doi: 10.1021/acs.biochem.6b01049. Epub 2017 Mar 2. Biochemistry. 2017. PMID: 28156101

4

Kinetic Analyses of the Siderophore Biosynthesis Inhibitor Salicyl-AMS and Analogues as MbtA Inhibitors and Antimycobacterial Agents.

Bythrow GV, Mohandas P, Guney T, Standke LC, Germain GA, Lu X, Ji C, Levendosky K, Chavadi SS, Tan DS, Quadri LEN. Bythrow GV, et al. Among authors: quadri len. Biochemistry. 2019 Feb 12;58(6):833-847. doi: 10.1021/acs.biochem.8b01153. Epub 2019 Jan 10. Biochemistry. 2019. PMID: 30582694 Free PMC article.

5

Mycobacterium abscessus Mutants with a Compromised Functional Link between the Type VII ESX-3 System and an Iron Uptake Mechanism Reliant on an Unusual Mycobactin Siderophore.

Bythrow GV, Farhat MF, Levendosky K, Mohandas P, Germain GA, Yoo B, Quadri LEN. Bythrow GV, et al. Among authors: quadri len. Pathogens. 2022 Aug 23;11(9):953. doi: 10.3390/pathogens11090953. Pathogens. 2022. PMID: 36145386 Free PMC article.

6

Comprehensive essentiality analysis of the Mycobacterium kansasii genome by saturation transposon mutagenesis and deep sequencing.

Levendosky K, Janisch N, Quadri LEN. Levendosky K, et al. Among authors: quadri len. mBio. 2023 Aug 31;14(4):e0057323. doi: 10.1128/mbio.00573-23. Epub 2023 Jun 23. mBio. 2023. PMID: 37350613 Free PMC article.

7

Inactivation of tesA reduces cell wall lipid production and increases drug susceptibility in mycobacteria.

Chavadi SS, Edupuganti UR, Vergnolle O, Fatima I, Singh SM, Soll CE, Quadri LE. Chavadi SS, et al. J Biol Chem. 2011 Jul 15;286(28):24616-25. doi: 10.1074/jbc.M111.247601. Epub 2011 May 18. J Biol Chem. 2011. PMID: 21592957 Free PMC article.

8

Mutational and phylogenetic analyses of the mycobacterial mbt gene cluster.

Chavadi SS, Stirrett KL, Edupuganti UR, Vergnolle O, Sadhanandan G, Marchiano E, Martin C, Qiu WG, Soll CE, Quadri LE. Chavadi SS, et al. J Bacteriol. 2011 Nov;193(21):5905-13. doi: 10.1128/JB.05811-11. Epub 2011 Aug 26. J Bacteriol. 2011. PMID: 21873494 Free PMC article.

9

Production of mycobacterial cell wall glycopeptidolipids requires a member of the MbtH-like protein family.

Tatham E, Sundaram Chavadi S, Mohandas P, Edupuganti UR, Angala SK, Chatterjee D, Quadri LE. Tatham E, et al. BMC Microbiol. 2012 Jun 22;12:118. doi: 10.1186/1471-2180-12-118. BMC Microbiol. 2012. PMID: 22726990 Free PMC article.

10

Biosynthesis of mycobacterial lipids by polyketide synthases and beyond.

Quadri LE. Quadri LE. Crit Rev Biochem Mol Biol. 2014 May-Jun;49(3):179-211. doi: 10.3109/10409238.2014.896859. Epub 2014 Mar 14. Crit Rev Biochem Mol Biol. 2014. PMID: 24625105 Review.

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