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Using exposure bands for rapid decision making in the RISK21 tiered exposure assessment.
Dellarco M, Zaleski R, Gaborek BJ, Qian H, Bellin CA, Egeghy P, Heard N, Jolliet O, Lander DR, Sunger N, Stylianou KS, Tanir JY. Dellarco M, et al. Among authors: qian h. Crit Rev Toxicol. 2017 Apr;47(4):317-341. doi: 10.1080/10408444.2016.1270255. Epub 2017 Feb 10. Crit Rev Toxicol. 2017. PMID: 28266262 Free PMC article. Review.
Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies.
Lowe K, Dawson J, Phillips K, Minucci J, Wambaugh JF, Qian H, Ramanarayanan T, Egeghy P, Ingle B, Brunner R, Mendez E, Embry M, Tan YM. Lowe K, et al. Among authors: qian h. Regul Toxicol Pharmacol. 2021 Dec;127:105073. doi: 10.1016/j.yrtph.2021.105073. Epub 2021 Oct 29. Regul Toxicol Pharmacol. 2021. PMID: 34743952 Free PMC article.
PBPK model reporting template for chemical risk assessment applications.
Tan YM, Chan M, Chukwudebe A, Domoradzki J, Fisher J, Hack CE, Hinderliter P, Hirasawa K, Leonard J, Lumen A, Paini A, Qian H, Ruiz P, Wambaugh J, Zhang F, Embry M. Tan YM, et al. Among authors: qian h. Regul Toxicol Pharmacol. 2020 Aug;115:104691. doi: 10.1016/j.yrtph.2020.104691. Epub 2020 Jun 2. Regul Toxicol Pharmacol. 2020. PMID: 32502513 Free PMC article. Review.
Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment.
Tan YM, Barton HA, Boobis A, Brunner R, Clewell H, Cope R, Dawson J, Domoradzki J, Egeghy P, Gulati P, Ingle B, Kleinstreuer N, Lowe K, Lowit A, Mendez E, Miller D, Minucci J, Nguyen J, Paini A, Perron M, Phillips K, Qian H, Ramanarayanan T, Sewell F, Villanueva P, Wambaugh J, Embry M. Tan YM, et al. Among authors: qian h. Regul Toxicol Pharmacol. 2021 Dec;127:105070. doi: 10.1016/j.yrtph.2021.105070. Epub 2021 Oct 28. Regul Toxicol Pharmacol. 2021. PMID: 34718074 Free PMC article.
4,758 results