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Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance.
Zhou M, Shao J, Wu CY, Shu L, Dong W, Liu Y, Chen M, Wynn RM, Wang J, Wang J, Gui WJ, Qi X, Lusis AJ, Li Z, Wang W, Ning G, Yang X, Chuang DT, Wang Y, Sun H. Zhou M, et al. Among authors: qi x. Diabetes. 2019 Sep;68(9):1730-1746. doi: 10.2337/db18-0927. Epub 2019 Jun 5. Diabetes. 2019. PMID: 31167878 Free PMC article.
Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase.
Tso SC, Qi X, Gui WJ, Chuang JL, Morlock LK, Wallace AL, Ahmed K, Laxman S, Campeau PM, Lee BH, Hutson SM, Tu BP, Williams NS, Tambar UK, Wynn RM, Chuang DT. Tso SC, et al. Among authors: qi x. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9728-33. doi: 10.1073/pnas.1303220110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716694 Free PMC article.
Staurosporine targets the Hippo pathway to inhibit cell growth.
Ma X, Li P, Chen P, Li J, Huang H, Wang C, Li W, Ding J, Zhao Y, Yu FX, Qi X, Zhang L. Ma X, et al. Among authors: qi x. J Mol Cell Biol. 2018 Jun 1;10(3):267-269. doi: 10.1093/jmcb/mjy016. J Mol Cell Biol. 2018. PMID: 29562261 No abstract available.
5-IP7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Zhang X, Li N, Zhang J, Zhang Y, Yang X, Luo Y, Zhang B, Xu Z, Zhu Z, Yang X, Yan Y, Lin B, Wang S, Chen D, Ye C, Ding Y, Lou M, Wu Q, Hou Z, Zhang K, Liang Z, Wei A, Wang B, Wang C, Jiang N, Zhang W, Xiao G, Ma C, Ren Y, Qi X, Han W, Wang C, Rao F. Zhang X, et al. Among authors: qi x. Nat Metab. 2021 Oct;3(10):1400-1414. doi: 10.1038/s42255-021-00468-7. Epub 2021 Oct 18. Nat Metab. 2021. PMID: 34663975
9,058 results