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Page 1
Inhibition of PIM Kinases in DLBCL Targets MYC Transcriptional Program and Augments the Efficacy of Anti-CD20 Antibodies.
Szydłowski M, Garbicz F, Jabłońska E, Górniak P, Komar D, Pyrzyńska B, Bojarczuk K, Prochorec-Sobieszek M, Szumera-Ciećkiewicz A, Rymkiewicz G, Cybulska M, Statkiewicz M, Gajewska M, Mikula M, Gołas A, Domagała J, Winiarska M, Graczyk-Jarzynka A, Białopiotrowicz E, Polak A, Barankiewicz J, Puła B, Pawlak M, Nowis D, Golab J, Tomirotti AM, Brzózka K, Pacheco-Blanco M, Kupcova K, Green MR, Havranek O, Chapuy B, Juszczyński P. Szydłowski M, et al. Among authors: pyrzynska b. Cancer Res. 2021 Dec 1;81(23):6029-6043. doi: 10.1158/0008-5472.CAN-21-1023. Epub 2021 Oct 8. Cancer Res. 2021. PMID: 34625423
Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies.
Winiarska M, Bojarczuk K, Pyrzynska B, Bil J, Siernicka M, Dwojak M, Bobrowicz M, Miazek N, Zapala P, Zagozdzon A, Krol M, Syta A, Podszywalow-Bartnicka P, Pilch Z, Dabrowska-Iwanicka A, Juszczynski P, Efremov DG, Slabicki M, Zenz T, Le Roy A, Olive D, Rygiel TP, Leusen JH, Golab J. Winiarska M, et al. Among authors: pyrzynska b. MAbs. 2014;6(5):1300-13. doi: 10.4161/mabs.32106. Epub 2014 Oct 30. MAbs. 2014. PMID: 25517315 Free PMC article.
Dissection of CD20 regulation in lymphoma using RNAi.
Słabicki M, Lee KS, Jethwa A, Sellner L, Sacco F, Walther T, Hüllein J, Dietrich S, Wu B, Lipka DB, Oakes CC, Mamidi S, Pyrzyńska B, Winiarska M, Oleś M, Seifert M, Plass C, Kirschfink M, Boettcher M, Gołąb J, Huber W, Fröhling S, Zenz T. Słabicki M, et al. Among authors: pyrzynska b. Leukemia. 2016 Dec;30(12):2409-2412. doi: 10.1038/leu.2016.230. Epub 2016 Aug 18. Leukemia. 2016. PMID: 27560109 No abstract available.
HDAC6 inhibition upregulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies.
Bobrowicz M, Dwojak M, Pyrzynska B, Stachura J, Muchowicz A, Berthel E, Dalla-Venezia N, Kozikowski M, Siernicka M, Miazek N, Zapala P, Domagala A, Bojarczuk K, Malenda A, Barankiewicz J, Graczyk-Jarzynka A, Zagozdzon A, Gabrysiak M, Diaz JJ, Karp M, Lech-Maranda E, Firczuk M, Giannopoulos K, Efremov DG, Laurenti L, Baatout D, Frenzel L, Malinowska A, Slabicki M, Zenz T, Zerrouqi A, Golab J, Winiarska M. Bobrowicz M, et al. Among authors: pyrzynska b. Blood. 2017 Oct 5;130(14):1628-1638. doi: 10.1182/blood-2016-08-736066. Epub 2017 Aug 22. Blood. 2017. PMID: 28830887 Free article.
FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy.
Pyrzynska B, Dwojak M, Zerrouqi A, Morlino G, Zapala P, Miazek N, Zagozdzon A, Bojarczuk K, Bobrowicz M, Siernicka M, Machnicki MM, Gobessi S, Barankiewicz J, Lech-Maranda E, Efremov DG, Juszczynski P, Calado D, Golab J, Winiarska M. Pyrzynska B, et al. Oncoimmunology. 2018 Jan 25;7(5):e1423183. doi: 10.1080/2162402X.2017.1423183. eCollection 2018. Oncoimmunology. 2018. PMID: 29721381 Free PMC article.
Inhibition of SYK or BTK augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large B-cell lymphoma.
Sasi BK, Martines C, Xerxa E, Porro F, Kalkan H, Fazio R, Turkalj S, Bojnik E, Pyrzynska B, Stachura J, Zerrouqi A, Bobrowicz M, Winiarska M, Priebe V, Bertoni F, Mansouri L, Rosenquist R, Efremov DG. Sasi BK, et al. Among authors: pyrzynska b. Leukemia. 2019 Oct;33(10):2416-2428. doi: 10.1038/s41375-019-0442-8. Epub 2019 Mar 14. Leukemia. 2019. PMID: 30872780
Cholesterol restricts lymphotoxin β receptor-triggered NF-κB signaling.
Banach-Orłowska M, Wyszyńska R, Pyrzyńska B, Maksymowicz M, Gołąb J, Miączyńska M. Banach-Orłowska M, et al. Among authors: pyrzynska b. Cell Commun Signal. 2019 Dec 26;17(1):171. doi: 10.1186/s12964-019-0460-1. Cell Commun Signal. 2019. PMID: 31878945 Free PMC article.
Targeting arginase-1 exerts antitumor effects in multiple myeloma and mitigates bortezomib-induced cardiotoxicity.
Ramji K, Grzywa TM, Sosnowska A, Paterek A, Okninska M, Pilch Z, Barankiewicz J, Garbicz F, Borg K, Bany-Laszewicz U, Zerrouqi A, Pyrzynska B, Rodziewicz-Lurzynska A, Papiernik D, Sklepkiewicz P, Kedzierska H, Staruch A, Sadowski R, Ciepiela O, Lech-Maranda E, Juszczynski P, Mackiewicz U, Maczewski M, Nowis D, Golab J. Ramji K, et al. Among authors: pyrzynska b. Sci Rep. 2022 Nov 16;12(1):19660. doi: 10.1038/s41598-022-24137-1. Sci Rep. 2022. PMID: 36385153 Free PMC article.
32 results