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Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors.
Jeschke J, Collignon E, Al Wardi C, Krayem M, Bizet M, Jia Y, Garaud S, Wimana Z, Calonne E, Hassabi B, Morandini R, Deplus R, Putmans P, Dube G, Singh NK, Koch A, Shostak K, Rizzotto L, Ross RL, Desmedt C, Bareche Y, Rothé F, Lehmann-Che J, Duterque-Coquillaud M, Leroy X, Menschaert G, Teixeira L, Guo M, Limbach PA, Close P, Chariot A, Leucci E, Ghanem G, Yuan BF, Willard-Gallo K, Sotiriou C, Marine JC, Fuks F. Jeschke J, et al. Among authors: putmans p. Nat Cancer. 2021 Jun;2(6):611-628. doi: 10.1038/s43018-021-00223-7. Epub 2021 Jun 23. Nat Cancer. 2021. PMID: 35121941 Free PMC article.
TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression.
Bonvin E, Radaelli E, Bizet M, Luciani F, Calonne E, Putmans P, Nittner D, Singh NK, Santagostino SF, Petit V, Larue L, Marine JC, Fuks F. Bonvin E, et al. Among authors: putmans p. Cancer Res. 2019 Feb 1;79(3):482-494. doi: 10.1158/0008-5472.CAN-18-1214. Epub 2018 Dec 11. Cancer Res. 2019. PMID: 30538121 Free PMC article.
Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation.
Lan J, Rajan N, Bizet M, Penning A, Singh NK, Guallar D, Calonne E, Li Greci A, Bonvin E, Deplus R, Hsu PJ, Nachtergaele S, Ma C, Song R, Fuentes-Iglesias A, Hassabi B, Putmans P, Mies F, Menschaert G, Wong JJL, Wang J, Fidalgo M, Yuan B, Fuks F. Lan J, et al. Among authors: putmans p. Nat Commun. 2020 Oct 2;11(1):4956. doi: 10.1038/s41467-020-18729-6. Nat Commun. 2020. PMID: 33009383 Free PMC article.
MicroRNAs regulate KDM5 histone demethylases in breast cancer cells.
Denis H, Van Grembergen O, Delatte B, Dedeurwaerder S, Putmans P, Calonne E, Rothé F, Sotiriou C, Fuks F, Deplus R. Denis H, et al. Among authors: putmans p. Mol Biosyst. 2016 Feb;12(2):404-13. doi: 10.1039/c5mb00513b. Mol Biosyst. 2016. PMID: 26621457
Portraying breast cancers with long noncoding RNAs.
Van Grembergen O, Bizet M, de Bony EJ, Calonne E, Putmans P, Brohée S, Olsen C, Guo M, Bontempi G, Sotiriou C, Defrance M, Fuks F. Van Grembergen O, et al. Among authors: putmans p. Sci Adv. 2016 Sep 2;2(9):e1600220. doi: 10.1126/sciadv.1600220. eCollection 2016 Sep. Sci Adv. 2016. PMID: 27617288 Free PMC article.
Comprehensive identification of long noncoding RNAs in colorectal cancer.
James de Bony E, Bizet M, Van Grembergen O, Hassabi B, Calonne E, Putmans P, Bontempi G, Fuks F. James de Bony E, et al. Among authors: putmans p. Oncotarget. 2018 Jun 12;9(45):27605-27629. doi: 10.18632/oncotarget.25218. eCollection 2018 Jun 12. Oncotarget. 2018. PMID: 29963224 Free PMC article.
DNA methylation profiling reveals a predominant immune component in breast cancers.
Dedeurwaerder S, Desmedt C, Calonne E, Singhal SK, Haibe-Kains B, Defrance M, Michiels S, Volkmar M, Deplus R, Luciani J, Lallemand F, Larsimont D, Toussaint J, Haussy S, Rothé F, Rouas G, Metzger O, Majjaj S, Saini K, Putmans P, Hames G, van Baren N, Coulie PG, Piccart M, Sotiriou C, Fuks F. Dedeurwaerder S, et al. Among authors: putmans p. EMBO Mol Med. 2011 Dec;3(12):726-41. doi: 10.1002/emmm.201100801. Epub 2011 Nov 16. EMBO Mol Med. 2011. PMID: 21910250 Free PMC article.
RNA biochemistry. Transcriptome-wide distribution and function of RNA hydroxymethylcytosine.
Delatte B, Wang F, Ngoc LV, Collignon E, Bonvin E, Deplus R, Calonne E, Hassabi B, Putmans P, Awe S, Wetzel C, Kreher J, Soin R, Creppe C, Limbach PA, Gueydan C, Kruys V, Brehm A, Minakhina S, Defrance M, Steward R, Fuks F. Delatte B, et al. Among authors: putmans p. Science. 2016 Jan 15;351(6270):282-5. doi: 10.1126/science.aac5253. Science. 2016. PMID: 26816380 Free article.
16 results