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De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma.
Shi DD, Savani MR, Levitt MM, Wang AC, Endress JE, Bird CE, Buehler J, Stopka SA, Regan MS, Lin YF, Puliyappadamba VT, Gao W, Khanal J, Evans L, Lee JH, Guo L, Xiao Y, Xu M, Huang B, Jennings RB, Bonal DM, Martin-Sandoval MS, Dang T, Gattie LC, Cameron AB, Lee S, Asara JM, Kornblum HI, Mak TW, Looper RE, Nguyen QD, Signoretti S, Gradl S, Sutter A, Jeffers M, Janzer A, Lehrman MA, Zacharias LG, Mathews TP, Losman JA, Richardson TE, Cahill DP, DeBerardinis RJ, Ligon KL, Xu L, Ly P, Agar NYR, Abdullah KG, Harris IS, Kaelin WG Jr, McBrayer SK. Shi DD, et al. Among authors: puliyappadamba vt. Cancer Cell. 2022 Sep 12;40(9):939-956.e16. doi: 10.1016/j.ccell.2022.07.011. Epub 2022 Aug 18. Cancer Cell. 2022. PMID: 35985343 Free PMC article.
The role of NF-κB in the pathogenesis of glioma.
Puliyappadamba VT, Hatanpaa KJ, Chakraborty S, Habib AA. Puliyappadamba VT, et al. Mol Cell Oncol. 2014 Dec 23;1(3):e963478. doi: 10.4161/23723548.2014.963478. eCollection 2014 Jul-Sep. Mol Cell Oncol. 2014. PMID: 27308348 Free PMC article. Review.
EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma.
Li L, Puliyappadamba VT, Chakraborty S, Rehman A, Vemireddy V, Saha D, Souza RF, Hatanpaa KJ, Koduru P, Burma S, Boothman DA, Habib AA. Li L, et al. Among authors: puliyappadamba vt. Oncogene. 2015 Jan 2;34(1):129-134. doi: 10.1038/onc.2013.534. Epub 2013 Dec 23. Oncogene. 2015. PMID: 24362532 Free PMC article.
An EGFR wild type-EGFRvIII-HB-EGF feed-forward loop regulates the activation of EGFRvIII.
Li L, Chakraborty S, Yang CR, Hatanpaa KJ, Cipher DJ, Puliyappadamba VT, Rehman A, Jiwani AJ, Mickey B, Madden C, Raisanen J, Burma S, Saha D, Wang Z, Pingle SC, Kesari S, Boothman DA, Habib AA. Li L, et al. Among authors: puliyappadamba vt. Oncogene. 2014 Aug 14;33(33):4253-64. doi: 10.1038/onc.2013.400. Epub 2013 Sep 30. Oncogene. 2014. PMID: 24077285 Free PMC article.
Cytoplasmic TRADD confers a worse prognosis in glioblastoma.
Chakraborty S, Li L, Tang H, Xie Y, Puliyappadamba VT, Raisanen J, Burma S, Boothman DA, Cochran B, Wu J, Habib AA. Chakraborty S, et al. Among authors: puliyappadamba vt. Neoplasia. 2013 Aug;15(8):888-97. doi: 10.1593/neo.13608. Neoplasia. 2013. PMID: 23908590 Free PMC article.
17 results