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Page 1
Efficient clinical-grade γ-retroviral vector purification by high-speed centrifugation for CAR T cell manufacturing.
Mekkaoui L, Tejerizo JG, Abreu S, Rubat L, Nikoniuk A, Macmorland W, Horlock C, Matsumoto S, Williams S, Smith K, Price J, Srivastava S, Hussain R, Banani MA, Day W, Stevenson E, Madigan M, Chen J, Khinder R, Miah S, Walker S, Ade-Onojobi M, Domining S, Sillibourne J, Sabatino M, Slepushkin V, Farzaneh F, Pule M. Mekkaoui L, et al. Among authors: pule m. Mol Ther Methods Clin Dev. 2022 Dec 9;28:116-128. doi: 10.1016/j.omtm.2022.12.006. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2022. PMID: 36620071 Free PMC article.
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR.
Kokalaki E, Ma B, Ferrari M, Grothier T, Hazelton W, Manzoor S, Costu E, Taylor J, Bulek A, Srivastava S, Gannon I, Jha R, Gealy R, Stanczuk L, Rizou T, Robson M, El-Kholy M, Baldan V, Righi M, Sillibourne J, Thomas S, Onuoha S, Cordoba S, Pule M. Kokalaki E, et al. Among authors: pule m. Mol Ther. 2023 Jul 5;31(7):2089-2104. doi: 10.1016/j.ymthe.2023.03.020. Epub 2023 Mar 21. Mol Ther. 2023. PMID: 36945773 Free article.
Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2.
Taylor J, Bulek A, Gannon I, Robson M, Kokalaki E, Grothier T, McKenzie C, El-Kholy M, Stavrou M, Traynor-White C, Lim WC, Panagiotou P, Srivastava S, Baldan V, Sillibourne J, Ferrari M, Pule M, Thomas S. Taylor J, et al. Among authors: pule m. Front Immunol. 2023 Jun 2;14:1119350. doi: 10.3389/fimmu.2023.1119350. eCollection 2023. Front Immunol. 2023. PMID: 37334382 Free PMC article.
Large-scale manufacturing of base-edited chimeric antigen receptor T cells.
Woodruff R, Parekh F, Lamb K, Mekkaoui L, Allen C, Smetanova K, Huang J, Williams A, Toledo GS, Lilova K, Roddie C, Sillibourne J, Pule M. Woodruff R, et al. Among authors: pule m. Mol Ther Methods Clin Dev. 2023 Oct 5;31:101123. doi: 10.1016/j.omtm.2023.101123. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 37886606 Free PMC article.
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR.
Kokalaki E, Ma B, Ferrari M, Grothier T, Hazelton W, Manzoor S, Costu E, Taylor J, Bulek A, Srivastava S, Gannon I, Jha R, Gealy R, Stanczuk L, Rizou T, Robson M, El-Kholy M, Baldan V, Righi M, Sillibourne J, Thomas S, Onuoha S, Cordoba S, Pule M. Kokalaki E, et al. Among authors: pule m. Mol Ther. 2024 Feb 7;32(2):556-558. doi: 10.1016/j.ymthe.2023.12.006. Epub 2023 Dec 15. Mol Ther. 2024. PMID: 38103549 Free article. No abstract available.
Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia.
Anderson ND, Birch J, Accogli T, Criado I, Khabirova E, Parks C, Wood Y, Young MD, Porter T, Richardson R, Albon SJ, Popova B, Lopes A, Wynn R, Hough R, Gohil SH, Pule M, Amrolia PJ, Behjati S, Ghorashian S. Anderson ND, et al. Among authors: pule m. Nat Med. 2023 Jul;29(7):1700-1709. doi: 10.1038/s41591-023-02415-3. Epub 2023 Jul 6. Nat Med. 2023. PMID: 37407840 Free PMC article.
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies.
Ferrari M, Righi M, Baldan V, Wawrzyniecka P, Bulek A, Kinna A, Ma B, Bughda R, Akbar Z, Srivastava S, Gannon I, Robson M, Sillibourne J, Jha R, El-Kholy M, Amin OM, Kokalaki E, Banani MA, Hussain R, Day W, Lim WC, Ghongane P, Hopkins JR, Jungherz D, Herling M, Welin M, Surade S, Dyson M, McCafferty J, Logan D, Cordoba S, Thomas S, Sewell A, Maciocia P, Onuoha S, Pule M. Ferrari M, et al. Among authors: pule m. Nat Commun. 2024 Feb 21;15(1):1583. doi: 10.1038/s41467-024-45854-3. Nat Commun. 2024. PMID: 38383515 Free PMC article.
Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein-Protein Interaction.
Jha R, Kinna A, Hotblack A, Bughda R, Bulek A, Gannon I, Ilca T, Allen C, Lamb K, Dolor A, Scott I, Parekh F, Sillibourne J, Cordoba S, Onuoha S, Thomas S, Ferrari M, Pule M. Jha R, et al. Among authors: pule m. ACS Chem Biol. 2024 Feb 16;19(2):308-324. doi: 10.1021/acschembio.3c00521. Epub 2024 Jan 20. ACS Chem Biol. 2024. PMID: 38243811 Free PMC article.
120 results