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Page 1
Neutrophil extracellular traps mediate bone erosion in rheumatoid arthritis by enhancing RANKL-induced osteoclastogenesis.
Schneider AH, Taira TM, Públio GA, da Silva Prado D, Donate Yabuta PB, Dos Santos JC, Machado CC, de Souza FFL, Rodrigues Venturini LG, de Oliveira RDR, Cunha TM, Alves-Filho JC, Louzada-Júnior P, Aparecida da Silva T, Fukada SY, Cunha FQ. Schneider AH, et al. Among authors: publio ga. Br J Pharmacol. 2024 Feb;181(3):429-446. doi: 10.1111/bph.16227. Epub 2023 Sep 28. Br J Pharmacol. 2024. PMID: 37625900
The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils.
Toller-Kawahisa JE, Hiroki CH, Silva CMS, Nascimento DC, Públio GA, Martins TV, Damasceno LEA, Veras FP, Viacava PR, Sukesada FY, Day EA, Zotta A, Ryan TAJ, Moreira da Silva R, Cunha TM, Lopes NP, Cunha FQ, O'Neill LAJ, Alves-Filho JC. Toller-Kawahisa JE, et al. Among authors: publio ga. Nat Commun. 2023 Jul 17;14(1):4280. doi: 10.1038/s41467-023-40021-6. Nat Commun. 2023. PMID: 37460614 Free PMC article.
S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/Type 3 Immunity.
Silva de Melo BM, Veras FP, Zwicky P, Lima D, Ingelfinger F, Martins TV, da Silva Prado D, Schärli S, Publio G, Hiroki CH, Melo PH, Saraiva A, Norbiato T, Lima L, Ryffel B, Vogl T, Roth J, Waisman A, Nakaya HI, da Silva Souza C, Cunha FQ, Cunha TM, Becher B, Alves-Filho JC. Silva de Melo BM, et al. Among authors: publio g. J Invest Dermatol. 2023 Sep;143(9):1678-1688.e8. doi: 10.1016/j.jid.2023.02.026. Epub 2023 Mar 13. J Invest Dermatol. 2023. PMID: 36921684
Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation.
Veras FP, Publio GA, Melo BM, Prado DS, Norbiato T, Cecilio NT, Hiroki C, Damasceno LEA, Jung R, Toller-Kawahisa JE, Martins TV, Assunção SF, Lima D, Alves MG, Vieira GV, Tavares LA, Alves-Rezende ALR, Karbach SH, Nakaya HI, Cunha TM, Souza CS, Cunha FQ, Sales KU, Waisman A, Alves-Filho JC. Veras FP, et al. Among authors: publio ga. Cell Rep. 2022 Dec 27;41(13):111897. doi: 10.1016/j.celrep.2022.111897. Cell Rep. 2022. PMID: 36577385 Free article.
Kallikrein 5 Inhibition by the Lympho-Epithelial Kazal-Type Related Inhibitor Hinders Matriptase-Dependent Carcinogenesis.
da Silva EZM, Fraga-Silva TFC, Yuan Y, Alves MG, Publio GA, da Fonseca CK, Kodama MH, Vieira GV, Candido MF, Innocentini LMAR, Miranda MG, da Silva AR, Alves-Filho JC, Bonato VLD, Iglesias-Bartolome R, Sales KU. da Silva EZM, et al. Among authors: publio ga. Cancers (Basel). 2021 Aug 31;13(17):4395. doi: 10.3390/cancers13174395. Cancers (Basel). 2021. PMID: 34503205 Free PMC article.