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Sulfated hyaluronic acid inhibits the hyaluronidase CEMIP and regulates the HA metabolism, proliferation and differentiation of fibroblasts.
Schmaus A, Rothley M, Schreiber C, Möller S, Roßwag S, Franz S, Garvalov BK, Thiele W, Spataro S, Herskind C, Prunotto M, Anderegg U, Schnabelrauch M, Sleeman J. Schmaus A, et al. Among authors: prunotto m. Matrix Biol. 2022 May;109:173-191. doi: 10.1016/j.matbio.2022.04.001. Epub 2022 Apr 8. Matrix Biol. 2022. PMID: 35405271
Glomerular Macrophages in Human Auto- and Allo-Immune Nephritis.
Moll S, Angeletti A, Scapozza L, Cavalli A, Ghiggeri GM, Prunotto M. Moll S, et al. Among authors: prunotto m. Cells. 2021 Mar 9;10(3):603. doi: 10.3390/cells10030603. Cells. 2021. PMID: 33803230 Free PMC article. Review.
DDR1 role in fibrosis and its pharmacological targeting.
Moll S, Desmoulière A, Moeller MJ, Pache JC, Badi L, Arcadu F, Richter H, Satz A, Uhles S, Cavalli A, Drawnel F, Scapozza L, Prunotto M. Moll S, et al. Among authors: prunotto m. Biochim Biophys Acta Mol Cell Res. 2019 Nov;1866(11):118474. doi: 10.1016/j.bbamcr.2019.04.004. Epub 2019 Apr 5. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30954571 Free article. Review.
New renal drug development to face chronic renal disease.
Moll S, Meier M, Formentini I, Pomposiello S, Prunotto M. Moll S, et al. Among authors: prunotto m. Expert Opin Drug Discov. 2014 Dec;9(12):1471-85. doi: 10.1517/17460441.2014.956075. Epub 2014 Sep 6. Expert Opin Drug Discov. 2014. PMID: 25195802 Review.
Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease.
Wright MB, Varona Santos J, Kemmer C, Maugeais C, Carralot JP, Roever S, Molina J, Ducasa GM, Mitrofanova A, Sloan A, Ahmad A, Pedigo C, Ge M, Pressly J, Barisoni L, Mendez A, Sgrignani J, Cavalli A, Merscher S, Prunotto M, Fornoni A. Wright MB, et al. Among authors: prunotto m. Nat Commun. 2021 Aug 2;12(1):4662. doi: 10.1038/s41467-021-24890-3. Nat Commun. 2021. PMID: 34341345 Free PMC article.
87 results